What comes first, beta-amyloid plaques or thinking and memory problems?

The scientific community has long believed that beta-amyloid, a protein that can clump together and form sticky plaques in the brain, is the first sign of Alzheimer’s disease. Beta-amyloid then leads to other brain changes including neurodegeneration and eventually to thinking and memory problems. But a new study challenges that theory. The study suggests that subtle thinking and memory differences […]

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Key risk factors for teenage suicide

New Australian research has found that young people who report suicidal thoughts and who also experience auditory hallucinations and psychological distress are at the greatest risk of future suicide attempts. The study by researchers from QIMR Berghofer and The University of Queensland’s Centre for Clinical Research examined risk factors that prompted 12 to 17 year olds to transition from thinking […]

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IBIS-II study finds anastrozole reduces breast cancer rates for high risk postmenopausal women

The Queen Mary University of London professor leading an international breast cancer study says anastrozole—rather than tamoxifen—should be the preventive drug-of-choice for post-menopausal women at increased risk of developing the disease. Anastrozole, which inhibits the production of oestrogen in postmenopausal women, has been used to treat breast cancer in that group for more than 20 years. The first phase of […]

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Personalized brain maps could improve treatment for Parkinson’s disease, other neurological conditions

People with severe Parkinson’s disease or other neurological conditions that cause intractable symptoms such as uncontrollable shaking, muscle spasms, seizures, obsessive thoughts and compulsive behaviors are sometimes treated with electric stimulators placed inside the brain. Such stimulators are designed to interrupt aberrant signaling that causes the debilitating symptoms. The therapy, deep-brain stimulation, can provide relief to some people. But in […]

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First-ever quality measures aim to reduce diabetes complications

The Endocrine Society and Avalere Health introduced the first-ever quality measures to help healthcare providers assess how well they identify and care for older adults at greater risk of hypoglycemia—low blood sugar that can be a dangerous complication of diabetes treatment. A panel of diabetes experts published the quality measures, which focus on outpatient treatment for adults who are 65 […]

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New chemical treatment for bed nets could prevent more infections by overcoming mosquito resistance

With insecticide resistance eroding the life-saving power of bed nets—a major malaria-fighting tool—researchers reported today that in a clinical trial that involved distributing millions of treated nets to households across Uganda, far fewer children showed evidence of malaria parasites after sleeping under nets newly formulated to disarm a mosquito’s key resistance mechanisms. The results presented today at the Annual Meeting […]

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Bolstered mother-child bonds at heart of research

Known as ‘the thief that steals motherhood,” postpartum depression (PPD) not only obstructs a mother’s capacity for understanding and enjoying her baby, but puts children at risk for behavioral and cognitive problems. While treating PPD itself doesn’t always end up benefiting the mother/child relationship, Nursing professor Panagiota Tryphonopoulos is looking at ways to bolster this critical bond. “Everybody experiences parenting […]

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Incidence of early-onset gastric cancer increasing in the U.S.

(HealthDay)—The incidence of early-onset gastric cancer has been increasing in the United States, and it seems to be distinct clinically and genetically from late-onset gastric cancer, according to a study recently published in Surgery. John R. Bergquist, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues examined clinical and genomic characteristics and risk factors for early-onset versus late-onset gastric […]

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Mindfulness video game changes areas of the brain associated with attention

With an estimated 97 percent of adolescents playing video games in their free time, there is growing potential to design games as tools for attention-building instead of attention-busting. A research team at the Center for Healthy Minds at the University of Wisconsin–Madison and the University of California, Irvine, designed a video game to improve mindfulness in middle schoolers and found […]

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