Protein "on/off switch" controls breast cancer spread and immunotherapy response

Reviewed Despite their promise, immunotherapies fail to treat many cancers, including over 80% of some of the most advanced breast cancers. And many of those patients who do respond still experience metastases eventually. New research from Stanford University and the Arc Institute has revealed a better way to predict and improve patient responses. A team led by Lingyin Li, associate […]

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Study shows spinal cord injury causes acute and systemic muscle wasting: Severity depends on location of the injury

Acute spinal cord injury (SCI) patients lose body weight and muscle mass, despite being on a high-calorie diet while in the intensive care unit. Their muscle wasting is substantial and extends beyond what can explained by inactivity or denervation (loss of nerve supply) alone. Research led by The Ohio State University Wexner Medical Center and College of Medicine published in […]

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Emotional problems in young people were rising rapidly even before the pandemic

There was a substantial increase in emotional problems among young people in Wales in the years immediately before the pandemic, research from Cardiff University shows. In the article, “Trends in adolescent emotional problems in Wales between 2013 and 2019: the contribution of peer relationships,” published in the Journal of Child Psychology and Psychiatry, academics studied data collected from more than […]

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Enlarged spaces in infant brains linked to higher risk of autism, sleep problems

Throughout the day and night, cerebrospinal fluid (CSF) pulses through small fluid-filled channels surrounding blood vessels in the brain, called perivascular spaces, to flush out neuroinflammation and other neurological waste. A disruption to this vital process can lead to neurological dysfunction, cognitive decline, or developmental delays. For the first time, researchers Dea Garic, Ph.D., and Mark Shen, Ph.D., both at […]

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Air pollutants commonly found indoors could have an impact on creativity, scientists find

Air quality in the office may affect our level of creativity at work, scientists at Nanyang Technological University, Singapore (NTU Singapore) have found. Working with the global air filter manufacturer Camfil on a shared research project, the NTU Singapore scientists found in a study that high levels of volatile organic compounds—gases released from products such as detergents, pesticides, perfumes, aerosol […]

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COVID-19 hospitalization linked to greater long-term health risks than seasonal influenza

A study published in The Lancet Infectious Diseases reveals that the long-term risk of death and health adversities associated with coronavirus disease 2019 (COVID-19)-related hospitalization is higher than that associated with seasonal influenza-related hospitalization. Study: Long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study. Image Credit: Andrii Vodolazhskyi / Shutterstock Background Like severe acute respiratory syndrome coronavirus 2 […]

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Using AI to diagnose autism in children

A multi-institutional Korean team of child and adolescent psychologists, behavioral scientists, ophthalmologists and biomedical systems informatics specialists has found that deep-learning-based AI systems can accurately diagnose children with autism. In their study, reported in the journal JAMA Network Open, the group created an autism-diagnosing tool using a learning-based AI system and tested it on human subjects. Autism, known more formally […]

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