Treatment for: Low-Grade Glioma Day One Announces New FIREFLY-1 Data for Tovorafenib (DAY101) and Initiation of Rolling NDA Submission to FDA for Relapsed or Progressive Pediatric Low-Grade Glioma BRISBANE, Calif., June 04, 2023 (GLOBE NEWSWIRE) — Day One Biopharmaceuticals (Nasdaq: DAWN) (“Day One” or the “Company”), a clinical-stage biopharmaceutical Company dedicated to developing and commercializing targeted therapies for people of […]

A new episode of our podcast, “Show Me the Science,” has been posted. These episodes feature stories about groundbreaking research, as well as lifesaving and just plain cool stuff involving faculty, staff and students at Washington University School of Medicine in St. Louis. In this episode, we hear from two physician-scientists who have been leaders in the U.S. effort to […]

Before Anthony S. Fauci, MD, even spoke, he received a standing ovation. For 55 seconds, applause prevailed during the 2023 MD Commencement ceremony Monday, May 15, at Washington University in St. Louis. The graduates and their loved ones, along with faculty and staff, cheered for Fauci, who recently retired after 38 years as director of the National Institute of Allergy […]

Lupus and cardiovascular diseaseLupus and skin complicationsLupus and kidney diseaseLupus and infectionsLupus and metabolic syndromeLupus and cancerLupus and thyroid disordersLupus and fibromyalgiaLupus and mental healthReferencesFurther reading Comorbidities are common in people with lupus. The autoimmune disease increases the risk of complications such as cardiovascular disease, cancer, and even mental health illnesses. Here, we explore some of the most common comorbidities […]

Strategies to treat pain without triggering dangerous side effects such as euphoria and addiction have proven elusive. For decades, scientists have attempted to develop drugs that selectively activate one type of opioid receptor to treat pain while not activating another type of opioid receptor linked to addiction. Unfortunately, those compounds can cause a different unwanted effect: hallucinations. But a new […]

Defining computational neuroscienceThe evolution of computational neuroscienceComputational neuroscience in the twenty-first centurySome examples of computational neuroscienceThe SpiNNaker supercomputerFrontiers in computational neuroscienceReferencesFurther reading The human brain is a complex and unfathomable supercomputer. How it works is one of the ultimate mysteries of our time. Scientists working in the exciting field of computational neuroscience seek to unravel this mystery and, in the […]

Types of arachnoid cystsCause and symptomsEpidemiologyDiagnosis and treatmentReferencesFurther reading Arachnoid cysts (ACs) are benign, discrete pockets of CSF (cerebrospinal fluid) or CSF-like fluids, accounting for 1% of all intracranial space-occupying lesions. Commonly observed during childhood, ACs can be of two types – primary developmental cysts or secondary cysts. Image Credit: Triff/Shutterstock.com Common symptoms include headache, dizziness, and vomiting, among others. […]

Rheumatoid arthritis (RA)SynovectomiesJoint replacementArthrodesisAllo-arthroplastyReferences Further reading Rheumasurgery, also known as Rheumatoid Surgery, is concerned with the surgical treatment of patients suffering from rheumatic disorders and rheumatism. A Rheumasurgeon aims to improve patient function, limit disease progression, and relieve pain. Rheumasurgical interventions can include synovectomies, joint replacement, and repositioning of joints. Image Credit: Chinnapong/Shutterstock.com Rheumatoid arthritis (RA) Rheumatoid arthritis (RA) is a […]

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient’s own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer. Then, the patient’s stem cells are returned to the patient to help with recovery. But for a significant proportion of patients, the number of stem cells […]

Social isolation vs. lonelinessHow does loneliness affect the immune system?Immune dysregulation and lonelinessThe importance of reducing loneliness in the elderlyReferences Further reading  Humans are social creatures who yearn to interact with others and feel a sense of belonging in their social relationships. Loneliness, which arises when an individual does not experience the intimacy normally associated with these interactions, can cause a […]