High Lp(a) Tied to Higher Coronary Plaque, Progression

MANNHEIM — Patients with high lipoprotein(a) levels not only have an almost twofold higher coronary plaque burden than those with low levels but also a faster rate of plaque progression, an observational imaging study shows. This could explain the greater risk for major adverse cardiovascular events seen in patients with high lipoprotein(a) [Lp(a)] levels, suggests the research, presented at the […]

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Multiple sclerosis discovery IDs key factor that shapes your risk

University of Virginia School of Medicine scientists have discovered a key determinant of our risk for multiple sclerosis (MS), advancing efforts to prevent and better treat the disease. Researchers led by Mariano Garcia-Blanco, MD, Ph.D., chair of UVA’s Department of Microbiology, Immunology and Cancer Biology, identified a series of processes in our cells that suppresses our risk for developing multiple […]

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Brain tumors are cognitive parasites—how brain cancer hijacks neural circuits and causes cognitive decline

Researchers have long known that brain tumors, specifically a type of tumor called a glioma, can affect a person’s cognitive and physical function. Patients with glioblastoma, the most fatal type of brain tumor in adults, experience an especially drastic decline in quality of life. Glioblastomas are thought to impair normal brain functions by compressing and causing healthy tissue to swell, […]

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MS in Black People More Common Than Previously Thought

TOPLINE: United States residents continue to have the highest prevalence of multiple sclerosis (MS). However, new data show the disease is becoming more racially diverse, with a higher prevalence in Black people than previously thought. METHODOLOGY: Researchers applied a validated case-finding algorithm to health claims datasets from private, military, and public (Medicaid and Medicare) insurance programs They calculated the cumulative […]

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FDA approves lynparza for BRCA-mutated metastatic castration-resistant prostate cancer

The U.S. Food and Drug Administration approved Lynparza (olaparib) with abiraterone and prednisone (or prednisolone) for adult patients with deleterious or suspected deleterious BRCA-mutated, metastatic, castration-resistant prostate cancer (mCRPC). The approval was based on findings from the PROpel trial in which 796 patients with mCRPC were randomly assigned (1:1) to receive either Lynparza with abiraterone or placebo with abiraterone and […]

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Exposure to forever chemicals during pregnancy linked to increased risk of obesity in kids

The risks of exposure to “forever chemicals” start even before birth, a new study confirms, potentially setting up children for future health issues. Exposure to per- and polyfluoroalkyl substances (PFAS) during pregnancy was linked to slightly higher body mass indices and an increased risk of obesity in children, according to a new Environmental Health Perspectives study led by Brown University […]

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Vendor notebook: New generative AI tools for provider operations

With healthcare technology innovation driven to infuse artificial intelligence into myriad healthcare systems to improve costs, patient outcomes and employee experiences, it’s hard to see where the groundswell on generative AI tools in healthcare is going. “Given the nature of this technology and the significant resources required to make it work, I expect most organizations will need to align with […]

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Mum-of-two left in agony after not being able to wee properly for five years

The mum-of-two, from Ashford, Kent, discovered she could no longer urinate by herself following the birth of her daughter, Isla, in October 2012. “The doctors didn’t know what was wrong with me they hadn’t seen it before,” the teaching assistant said. “I could not empty my bladder,” Rachel revealed. “I couldn’t pass any urine at all.” Doctors found Rachel was […]

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Alabama study finds lack of timely follow-up after heart failure hospitalization for most adults with diabetes

More than half of Medicaid-covered adults in Alabama with type 2 diabetes did not receive follow-up health care within the recommended two-week period following hospitalization for newly-diagnosed heart failure, according to new research. The analysis, published today in the Journal of the American Heart Association, found worse follow up for African American and Hispanic adults. The large, racially diverse study […]

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