Has a treatment for Alzheimer’s been sitting on pharmacy shelves for decades? Scientists have two possible candidates

Two drugs approved decades ago not only counteract brain damage caused by Alzheimer’s disease in animal models, the same therapeutic combination may also improve cognition. Sounds like a slam dunk in terms of a cure—but not yet. Researchers currently are concentrating on animal studies amid implications that remain explosive: If a surprising drug combination continues to destroy a key feature […]

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COVID-19: The older you are, the more antibodies you have

With the emergence of SARS-CoV-2 variants worldwide, the pandemic’s spread is accelerating. A research team led by Joelle Pelletier and Jean-François Masson, both professors in Université de Montréal’s Department of Chemistry, wanted to find out whether natural infection or vaccination led to more protective antibodies being generated. In their study published today in Scientific Reports, they observe that those who […]

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It’s time to replace your smoke alarm batteries

(HealthDay)—Setting your clocks back an hour this Sunday also means it’s time to replace the batteries in your smoke detectors and carbon monoxide alarms, the U.S. Consumer Product Safety Commission (CPSC) says. Working alarms are especially important because people are spending more time at home due to the pandemic, which means furnaces, fireplaces and other fuel-burning appliances are being used […]

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Developing wound infection tests

The University of Bath and University Hospitals Bristol and Weston NHS Foundation Trust is launching a new spin-out company that is creating a quick and simple test for diagnosing bacterial infections in wounds, based on technology developed at the University’s Department of Chemistry. SmartWound Limited’s technology uses a color-changing dye to diagnose bacterial infections from wound swab samples, specifically detecting […]

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Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

The ongoing coronavirus disease 2019 (COVID-19) pandemic has claimed millions of lives, and there has been significant damage caused to the global economy. Despite the development of multiple highly effective vaccines, the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has not been halted due to breakthrough infections. Study: Mitoxantrone modulates a glycosaminoglycan-spike complex to inhibit SARS-CoV-2 infection. Image […]

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Britain should brace for ‘early’ flu outbreak that could kill 60,000 people, warn experts

WHO expert warns COVID-19 may ‘become worse than influenza’ We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info The confluence of influenza and coronavirus has fanned fears the UK […]

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Researchers detect a diffusion barrier inside fly brain

The neurons, located in the brain are interconnected in a complex pattern and establish special communication points, the synapses. All neurons require a constant environment in order to function reliably. To ensure this, the brain is surrounded by the so-called blood-brain barrier. It ensures, for example, that the nutrient balance always remains the same and that harmful influences do not […]

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New epigenetic editing technique may advance the treatment of many diseases

Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not "turning on" and "turning off" as they should. By using new CRISPR/Cas9 genome editing technology, in a recent paper in Nature Communications, McGill University researchers have described a new technique that scientists across the world can potentially use to explore novel ways […]

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