A new research paper titled “Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV” has been published in Aging. Despite effective antiretroviral therapy, cognitive impairment and other aging-related comorbidities are more prevalent in people with HIV (PWH) than in the general population. Previous research examining DNA methylation has shown PWH exhibit accelerated biological […]

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide. One key discovery of the study: Sugar appears to play a role in the formation of fluid-filled cysts that are PKD’s hallmark. In people, these cysts grow […]

Researchers published the study covered in this summary on Research Square as a preprint that has not yet been peer reviewed. Key Takeaways Among adults with type 2 diabetes, decreased levels of serum osteocalcin — a bone-derived hormone and a marker of bone formation — were associated with a worse cardiovascular risk profile in a new study. Serum osteocalcin levels were […]

Study findings out today in JAMA Network Open show an important step forward in treating the psychological injuries of war. Researchers report that treatment for combat-related post-traumatic stress disorder (PTSD), which affects hundreds of thousands of U.S. military personnel and veterans, can be both fast and effective for a majority of patients. Their study showed clinically significant reductions in PTSD […]

Researchers at Baylor College of Medicine have found more evidence that dry fasting (fasting without food or liquid intake) from dawn to dusk can play an important role in overall health. In a new study published in Metabolism Open, researchers found that fasting from dawn to dusk for four weeks has an anti-atherosclerotic, anti-inflammatory and anti-tumorigenic effect on the proteins […]

Matthew Stride was just 26 when he was given the ‘crushing’ news that he has an incurable malignant brain tumour. He was given five years to live in 2015, but has outlived his prognosis by two years. Now, he’s 33 and plans to run the London Marathon for charity. Matthew, from Sutton Coldfield, in Birmingham, said: ‘To get a prognosis of […]

In a recent study posted to the medRxiv* server, researchers conducted a multicenter, cross-sectional seroprevalence study in emergency departments of five hospitals in North Rhine-Westphalia, Germany, between August and September 2022. They assessed point seroprevalence and neutralization activity against Wu01, BA.4/5, and BQ.1.1. Study: Impaired humoral immunity to BQ.1.1 in convalescent and vaccinated patients. Image Credit: Naeblys/Shutterstock Background Of these […]

Desperate families searching for critical COVID-19 medication in China, faced with bare pharmacy shelves and an explosion of cases, are being driven into murky online marketplaces rife with price gouging and fraud. Beijing last month abruptly tore down its hallmark zero-COVID virus containment policy, lifting widespread restrictions that had triggered nationwide protests and stifled the economy. The move unleashed a […]

In a recent study published in JAMA Network Open, researchers preliminarily evaluated the practicality of utilizing the United States (US) Food and Drug Administration (FDA)-advocated endpoints to assess the effectiveness of acupuncture in IBS-D (irritable bowel syndrome with diarrhea) management. Study: Acupuncture for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome A Pilot Randomized Clinical Trial. Image Credit: Africa Studio/Shutterstock Background […]

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune […]