FDA proposes overhaul of fast-track process for cancer meds

Illustration: Rebecca Zisser/Axios The Food and Drug Administration is eyeing policy changes that could make drugmakers conduct more stringent trials to win fast-track approvals of cancer drugs. Why it matters: The agency's accelerated approval process has drawn fire for the way it allows manufacturers to launch products based on preliminary evidence and charge high prices before they complete trials. Some […]

Continue reading »

University of Bath students building an artificial heart for the ‘Heart Hackathon’ competition

A team of University of Bath students are creating a working artificial heart as part of a worldwide ‘Heart Hackathon’ competition. Team Bath Heart members are aiming to represent the UK in the Heart Hackathon contest. Image Credit: University of Bath Team Bath Heart (TBH) is seeking to design, prototype and test a fully working artificial heart in the contest, […]

Continue reading »

Epigenome reprogramming after SARS-CoV-2 infection

In a recent article in published in the journal Nature Microbiology, researchers in Texas, United States (US) performed a three-dimensional (3D) evaluation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected human cells to show a direct cell-autonomous effect elicited by SARS-CoV-2 on the host chromatin. The study aimed at improving the understanding of coronavirus disease 2019 (COVID-19)-related perturbations in the […]

Continue reading »

Is severe tiredness 'chronic fatigue' or something else?

DR MARTIN SCURR: Is severe tiredness ‘chronic fatigue’ or something else? My daughter, now 40, had a traumatic birth six years ago — soon after she started feeling unnaturally tired. A private consultant diagnosed fibromyalgia, and she has ME. She has tried everything — acupuncture, counselling, reiki — but the fatigue is crippling. Name and address supplied. I understand your […]

Continue reading »

Hydroxyurea Underused in Youth With Sickle Cell Anemia

Even after endorsement in updated guidelines, hydroxyurea is substantially underused in youth with sickle cell anemia (SCA), new research indicates. SCA can lead to pain crises, stroke, and early death. Hydroxyurea, an oral disease-modifying medication, can reduce the complications. In 2014, the National Heart, Lung, and Blood Institute published revised guidelines that hydroxyurea should be offered as the primary therapy […]

Continue reading »

Baby left with cerebral palsy when medics dismissed mum's stomach pain

Baby boy was left with cerebral palsy after blundering hospital staff advised his pregnant mum to get a warm BATH when she complained of stomach pain Shanto Khaliquzzaman was starved of oxygen and developed cerebral palsy He was resuscitated at birth and spent 22 days on a ventilator in intensive care Birmingham Women’s and Children’s NHS Foundation Trust admitted liability  A […]

Continue reading »

How to rewire your brain to feel good on Mondays

If you hate Mondays, you’re most certainly in good company. After a couple of days off, many of us have difficulty settling back into our routines and work duties. You may even have dread and anxiety that seeps into the weekend in the form of “Sunday scaries”. You can’t always change your schedule or obligations to make Mondays more appealing, […]

Continue reading »

Largest study to date of minipuberty identifies two new patterns of the reproductive hormone, AMH, in infant girls

Minipuberty is a stage of reproductive development during infancy in both sexes when reproductive hormones change and reproductive organs develop. The importance of minipuberty is not well understood but could represent an opportunity for the early identification of future reproductive conditions and enable prompt treatment. Anti-Müllerian hormone (AMH) is one of the hormones that changes during minipuberty, and it plays […]

Continue reading »
1 180 181 182 183 184 1,322