In a recent study published in the journal Nature Microbiology, researchers investigated whether intestinal microbial alterations contribute to anorexia nervosa (AN) pathogenesis. AN, a disorder associated with altered eating, has caused considerable mortality, especially among women. However, therapies based on scientific evidence are scarce. AN pathogenesis likely involves several environmental and genetic factors. Studies have reported intestinal microbial dysbiosis among […]

Cancer survivors may be at long term heightened risk of subsequent cardiovascular disease, irrespective of traditional underlying risk factors, suggest the findings of a large UK Biobank study, published online in the journal Heart. Those with previous breast or blood cancers may be at greatest risk, the findings indicate. Shared vascular risk factors as well as the treatments and biological […]

Results from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of patients with rare cancers, are being reported for five cohorts of patients who had rare gynecologic cancers. In three of those five cohorts – the cohorts for clear cell ovarian cancer; small cell ovarian carcinoma, hypercalcemic type; and non-epithelial ovarian […]

A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose. The compound, which is described in an ACS Pharmacology & Translational Science paper published on April 17, 2023, and hasn't yet been studied in humans, works in a fundamentally different way than existing treatments […]

A score based on four readily available clinical and imaging parameters identifies the heart failure patients who benefit most from atrial fibrillation ablation, according to late-breaking science presented at EHRA 2023, a scientific congress of the European Society of Cardiology (ESC). Atrial fibrillation and heart failure often coexist. It is estimated that approximately 30% of patients with heart failure will […]

Photo: Emily Olsen / MobiHealthNews One of the key tenets of New York City-based Mount Sinai Health System’s remote patient monitoring program is choosing easy-to-use devices that don’t require extra technology on the patient’s end, said Cathleen Mathew, director of condition management and population health. The program, which went live in 2020, is largely focused on hypertension, but the health […]

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Obstructive sleep apnea (OSA) may be associated with early cognitive decline in middle-aged men, new research shows. In a pilot study out of King’s College London, participants with severe OSA experienced worse executive functioning as well as social and emotional recognition versus healthy controls. Major risk factors for OSA include obesity, high blood pressure, smoking, high cholesterol, and being middle-aged […]

Plants look so different from animals, that it’s easy for many people to think of them as alien and separate from us. Most people appreciate how pretty flowers and trees look and know photosynthesis is essential to life. But our mental and physical connection to plant life runs deeper than you might expect. The scientific evidence that plants play a […]

Photo: Sarah Silbiger/Getty Images An FDA expert panel on Thursday unanimously recommended that the U.S. overhaul its pandemic vaccine strategy and replace initial doses of original COVID shots with bivalent ones that target specific Omicron subvariants. The big picture: So far, the U.S. COVID vaccine strategy has been developed and revised on the fly, leading at time to public confusion. […]