MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

In a recent study published in Scientific Reports, researchers reported that microfibril-associated protein 5 (MFAP5) mediates wound healing through its pro-fibrotic effect by modulating collagen formation, angiogenesis, and fibroblast behavior. Study: Microfibril-associated protein 5 and the regulation of skin scar formation. Image Credit: David A Litman / Shutterstock.com Background While the regenerative capacity after any injury differs across species, wound healing […]

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FDA Flags Issues at China Plant for Cancer Drug

(Reuters) -Coherus BioSciences Inc said on Wednesday the U.S. Food and Drug Administration (FDA) had flagged three observations at its partner’s manufacturing site in China when the agency was conducting inspections related to its experimental cancer drug. However, the company said those observations, raised in Form 483, were “easily addressable”, adding that it planned to submit its response to the […]

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Q&A: More evidence needed to confirm promise of remote or decentralized trials

There’s one question that Hollings Cancer Center researcher Jennifer Dahne, Ph.D., co-director of the remote and virtual trials program at the South Carolina Clinical & Translational Research Institute, hears more than any other as she consults with clinical researchers about how to set up remote trials, also known as decentralized trials. Will these trials overcome the barriers that make it […]

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Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms and providing supportive care. Reporting June 1 in the journal Cell Stem Cell, researchers from Japan show in an early clinical trial that […]

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Patient With Blood Cancer Takes on Bias and Gaslighting

Paula Ngon, a 28-year-old public relations professional with Estée Lauder in New York, understands the value of good communication. After all, it’s her job to share information about her employer’s products with the world. Recently, she needed to tap her career training for another purpose: to capture the attention of a heedless oncologist. Diagnosed with Hodgkin lymphoma in 2021, Ms. […]

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