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Emotion-recognition among people with disorders such as Parkinson's disease or schizophrenia may be affected by changes in the levels of dopamine in the brain, say researchers at the University of Birmingham.

Dopamine is a chemical messenger – often known as the 'happy hormone' – that carries signals controlling mental and emotional responses in the brain.

Parkinson's disease and other neurological disorders are known for their links with low or disrupted dopamine levels that causes those affected to struggle with a number of social skills. This is the first time, however, that a positive connection has been made between dopamine and the ability to recognize emotions in others.

In a new study, published in the Journal of Neuroscience, a team in the University's Centre for Human Brain Health showed that manipulating levels of dopamine affected emotion recognition. More specifically, the research showed that while people with low baseline levels of the chemical messenger became better at emotion recognition after receiving a dopamine boost, those with higher baseline levels actually became worse.

The ability to recognize emotions in others is fundamental to our everyday social interactions and this is often atypical in people with neurological disorders. Our research shows that dopamine medication – even in small doses – can affect these abilities. That has important implications for fine-tuning a patient's medicine regime to ensure a balance between controlling their symptoms and preserving social functions."

Dr Bianca Schuster, generic risperdal online without prescription Lead Author

In the study, the team worked with 33 healthy male and female individuals and assessed their baseline dopamine levels. This was done by testing people's working memory, a well-recognized proxy for dopamine levels that avoids invasive brain imaging.

Individuals were asked to gauge the emotions of a series of figures in three different video clips in two separate tests. In the first they were given a dose of haloperidol, a drug affecting brain dopamine levels which is commonly used to treat schizophrenia, and in the second they were given a placebo. The figures were seen walking, in outline only, and in three different gaits and postures, denoting angry, happy and sad emotions.

Participants with a lower working memory, and so assumed lower baseline levels of dopamine, improved their emotion recognition under haloperidol, whereas those with a higher working memory became worse at emotion recognition under the drug.

"Individuals with low baseline dopamine also slowed their own walking pace under haloperidol, and so we think the effects of the drug on movement and emotion recognition are connected," says Dr Schuster. "It is not yet clear, however, why the drug actually impaired emotion recognition in the participants with high baseline dopamine. It's likely that timing and movement are not the only mechanisms that are important."

More work needs to be done to confirm whether these results predict the effects of dopamine in other emotion recognition tasks.