Triglycerides are the most common type of fat digested in the body and can be either consumed in the diet or produced in the body. They normally circulate in the bloodstream to supply energy to cells and are stored in body fat as an emergency store of energy. If there are excessive levels of triglycerides in the body, the level […]
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Fabry disease is a rare genetic condition that belongs to a group of disorders referred to as lysosomal storage disease. This condition is also called Anderson-Fabry disease, Fabry’s disease, angiokeratoma corporis diffusum and alpha-galactosidase A deficiency. The disease is named after a Johannes Fabry who discovered it. Disease inheritance Fabry disease is inherited in an X-linked manner, meaning the mutation […]
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Creatinine is a breakdown product of muscle metabolism. The main route of creatinine excretion is through the kidneys, where it is filtered by the glomerulus and also secreted by the proximal tubule. In a healthy kidney, there is little or no tubular reabsorption of creatinine. Creatinine is therefore a useful indicator of renal health because it is excreted in the […]
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Lactose intolerance is frequently and mistakenly self-diagnosed. In babies, it is also often confused with cow milk allergy. Diagnosis should not be based on clinical symptoms alone and should be made by a physician who has performed certain laboratory tests. Diagnosis outline Lactose intolerance is usually diagnosed in the following way: A patient is asked to maintain a food diary […]
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Antioxidants have a variety of uses in the industry. They are most commonly used as food preservatives and supplements. The industrial and other uses of antioxidants can be summarized as follows. Antioxidants as food preservatives Antioxidants are used to retard the oxidation of an organic substance. This increases the useful life or shelf life of that material. For example, in […]
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Rheumatoid arthritis treatment is outlined in several guidelines worldwide. These include guidelines from ACR, EULAR, and the UK’s National Institute for Health and Clinical Excellence. It is to be remembered that rheumatoid arthritis has no absolute cure. It is a progressive disease. However, there are several approaches that can help in preventing and delaying the progress of the disease as […]
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Two major side-effects of paclitaxel therapy are frequent hypersensitivity reactions and neuropathy. Standard paclitaxel contains Cremophor EL as a solvent, thus requiring premedication with high doses of antihistamines and corticosteroids, as well as prolonged infusion times. Albumin-bound or nab-paclitaxel was developed to overcome such limitations, and also to ensure more convenient drug administration and improve toxicity profiles. Hypersensitivity reactions Early […]
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Post-Traumatic Stress Disorder (PTSD) is a form of anxiety disorder caused by a distressing or traumatic life event. Some of the common risk factors for PTSD include: Being sexually or physically abused early in life Early military life Being a witness to or victim of a serious accident, fire, terrorist attack or natural disaster such as a flood or earthquake […]
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Whilst there are several reasons that the surgical removal of all or part of the ovaries may be indicated to benefit a woman, it is important that potential risks are considered. Oophorectomy is not the preferred method of prophylaxis from breast or ovarian cancer for every woman, as the potential risks are significant and must be weighed up against the […]
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Postpartum depression (Postnatal depression) is a type of depressive illness that some women experience after child birth. This form of depression usually occurs around 4 to 6 weeks after delivery but sometimes does not manifest until months after the baby is born. The condition can occur whether a woman gives birth naturally or by way of a caesarean section. The […]
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