The stem cells used in a transplant are collected from the blood or sometimes the bone marrow. The first step in preparation for collection is to move the stem cells into the blood from the bone marrow using a process called mobilization. The mobilization of stem cells is achieved through injections of growth factor for between 5 and 10 days. […]
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Skip to: What is osteoarthritis? What are the common complications of osteoarthritis? Living with osteoarthritis Osteoarthritis is a type of degenerative arthritis that most commonly affects joints in the hips, knees, lower back, neck, and fingers. The model of knee joint shown the process of osteoarthritis of knee and total knee replacement surgery. Image Credit: Peter Porrini / Shutterstock What […]
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Hypotonia results in loss of normal resting muscle tone. It is basically a symptom of some underlying disease. The condition is manifested as reduced resistance to passive movement of joints. Sources of hypotonia The defect may lie at the – Central nervous system Central hypotonia with defects at the brain or spinal cord Peripheral nerves (motor and/or sensory) Peripheral hypotonia […]
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Notwithstanding notable progress in medicine and biomedical science, parasitic diseases still represent a burden and a threat to human health. Among a myriad of parasitic diseases, those transmitted by vectors (mainly arthropods) play a significant role. Furthermore, such diseases are very prevalent in the poorest countries of the world, affecting an extensive portion of the human population, as well as […]
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Although Charcot-Marie-Tooth disease (CMT) is a lifelong condition with no known cure, the symptoms can be managed with appropriate therapies to increase independence and quality of life of the individual. As it is a progressive condition, regular check-ups are required to assess for any relevant changes in symptoms that may require specific attention. Additionally, the type of CMT will also […]
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Treatment of chronic myeloid leukemia aims at correcting blood counts in three months, clearing bone marrow of the cells containing Philadelphia chromosome by 12 months and taking the patient to a stage where the leukaemia can only be detected by a very sensitive molecular test by 18 months. Early treatments for CML Chronic myeloid leukemia is effectively treated early with […]
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Hypothyroidism is a disease of the thyroid gland that affects the amount of thyroxine produced by the gland. Management of this condition involves using hormone replacement therapy to replace this thyroxine. A synthetic form of thyroxine is available as a medication called levothyroxine, which can be taken as an oral tablet on a daily basis. At first, patients are given […]
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Primary ciliary dyskinesia (PCD) is a rare disease of childhood and the original ciliopathy to be identified. It leads to a variety of clinical manifestations, which often lead to a fatal outcome in early life. Early Signs and Symptoms The clinical features in PCD are due to three contributory factors, namely: Abnormal structure, function, or assembly of cilia which prevent […]
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Skip to What is a randomized controlled trial? What is a pilot study? Optimizing information from pilot studies Trial recruitment Protocol non-adherence U.S. POINTER randomized controlled trial assessed PET imaging to measure the buildup of amyloid and tau, two proteins whose accumulation in the brain has been linked to Alzheimer's dementia. Malachi Tran, University of California, Berkeley What is a […]
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Tay-Sachs Disease is a progressive and fatal genetic condition that involves a complete deficiency of the hexosaminidase-A (HEXA) enzyme. This enzyme is needed in healthy individuals for the process of hydrolysis of GM2 ganglioside to occur. For individuals with Tay-Sachs disease that lack this enzyme, the fatty substance of GM2 ganglioside accumulates in the brain and leads to the symptoms […]
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