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A peptide-drug conjugate that targets the acidic environment of cancer cells enhanced the efficacy of immune checkpoint inhibitors in preclinical cancer models, according to results presented at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics, held October 7-10, 2021. Immune checkpoint inhibitors are commonly combined with chemotherapy, but the myelosuppression associated with chemotherapy can reduce the efficacy […]

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A team of researchers working at the Indiana University School of Medicine, 5mg adderall 4 times a day has developed a compound that can degrade the cancer-promoting protein SUMO1. In their paper published in the journal Science Translational Medicine, the group describes their work in attempting to find a degrader for what has been described as an undruggable cancer-related protein. […]

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Eugene E. wasn’t looking for a dog when he found Foxie, but the time was suddenly right.  “I looked at one site—the ASPCA—and there was my dog,” Eugene recalls.  Having never adopted a dog before, Eugene filled out an application on the ASPCA website to see what the process was like. After Christmas of 2020, Eugene connected with Matchmakers for a phone […]

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Raspberries and almonds are the best foods for your health but instant noodles and chocolate puddings are the worst, according to scientists who’ve ranked 8,000 snacks and drinks New system ranks just over 8,000 food, drinks, and meals out of a score of 100 Raw fruits top the chart while instant meals and most desserts score just 1 point Creators […]

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Fox News Flash top headlines for October 20 Fox News Flash top headlines are here. Check out what’s clicking on Foxnews.com. The U.S. Food and Drug Administration (FDA) is expected to allow the mixing and matching of COVID-19 vaccine booster doses this week, according to reports. The forthcoming announcement by the agency is anticipated as the campaign for additional shots […]

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A Ludwig Cancer Research study has identified and preclinically validated combination treatments for the brain metastases of breast cancer, a common and typically lethal manifestation of the malignancy. The combination therapy, reported in the current issue of Nature Cancer, targets tumor-associated macrophages and microglia (TAMs), immune cells found within brain metastases that cancer cells can manipulate to support their growth […]

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(Reuters) – The European Union’s drug regulator said it was evaluating a marketing authorisation for an antibody cocktail developed by Roche and Regeneron for treatment and prevention of COVID-19 in people above the age of 12. The European Medicines Agency (EMA) said on Monday it will assess the risks and benefits of the drug, called Ronapreve, and it could issue […]

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FILE PHOTO: A healthcare worker prepares doses of the coronavirus disease (COVID-19) vaccine following Republican Governor Greg Abbott’s ban on COVID-19 vaccine mandates by any entity, including private employers, at Acres Home Multi-Service Center in Houston, Texas, U.S., October 13, acetaminophen codeine pill identifier 2021. REUTERS/Callaghan O’Hare(Reuters) – The United States has administered 410,189,737 doses of COVID-19 vaccines in the […]

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Like most other kids with covid, Dante and Michael DeMaino seemed to have no serious symptoms. Infected in mid-February, both lost their senses of taste and smell. Dante, 9, atarax sanego had a low-grade fever for a day or so. Michael, 13, had a "tickle in his throat," said their mother, Michele DeMaino, of Danvers, Massachusetts. At a follow-up appointment, […]

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