A study published in The Journal of Pathology reveals that many cancers that carry a poor prognosis express an altered form of human telomerase reverse transcriptase (hTERT), an enzyme that regulates the expression of multiple genes. Scientists previously linked a modification called phosphorylation at a particular location on the hTERT enzyme to poor prognosis in liver and pancreatic cancers. Now […]

Research published today in Nature Chemical Biology reveals new opportunities for using small molecule drugs to target KRAS, the most commonly mutated protein in cancer. Promega research scientists collaborated with the University of California – San Francisco research group led by Dr. Kevan M. Shokat, a global leader in KRAS biology, to study the binding of potentially therapeutic molecules to […]

Dr Hilary discusses ibuprofen as possible COVID-19 treatment We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info NHS guidance says: “It’s safe to take paracetamol with other types of […]

The US Food and Drug Administration (FDA) has approved donepezil transdermal system (Adlarity) for patients with mild, moderate, buy cheap zanaflex canada online or severe Alzheimer’s disease (AD), the manufacturer has announced. Adlarity is the first and only once-weekly patch to continuously deliver consistent doses of the acetylcholinesterase inhibitor through the skin, bypassing the digestive system and resulting in low […]

The future of public health looks set to become increasingly digital. The coronavirus disease 2019 (COVID-19) pandemic led to unprecedented disruption to both the global economy and healthcare.  This spurred a demand for digital transformation, particularly in the area of diagnosis and a need for digital surveillance and other solutions, such as telemedicine, to tend to patient needs. This article […]

NEW YORK (Reuters Health) – Treatment with the experimental drug donidalorsen cut the number of attacks over 17 weeks by 90% in people with hereditary angioedema, according to the results from a 20-patient randomized phase-2 trial. The six placebo recipients had an average of 2.21 attacks per month compared with 0.23 per month among the 14 volunteers who received four […]

Mark Ruffalo teases Marvel Cinematic Universe photoshoot We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info In 2001, Mark Ruffalo grabbed the attention of the on-set doctor for a […]

A French research team has developed a microRNA (miRNA) signature for diagnosing endometriosis through a simple saliva test. Its validation in a larger cohort could soon allow doctors to have a cheap, non-invasive, and accurate tool to use in diagnosing a disease that, for the time being, is difficult to identify with any certainty. The researchers suggest that their methodology could […]

Type 2 diabetes can be a 'devastating diagnosis' says expert We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Type 2 diabetes is characterised by a dysfunction in the […]

When clinical psychiatrist and University of Queensland researcher Dr. Cathy Franklin saw her first patient with Catatonia and Acute Regression in Down syndrome in 2009, she was shocked. The condition strikes young people with Down syndrome, who might previously have been active and high functioning, causing them to suddenly regress. “These young people can go from being able to talk, […]