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Changes in genomic copy number can also occur via whole-genome doubling (WGD) and chromothripsis. These evolutionary events may be rampant during tumor development and can transpire into the evolution of highly complex cancer genomes. Study: Signatures of copy number alterations in human cancer. Image Credit: Kjpargeter/Shutterstock Background Numerous factors can lead to gains or losses of deoxyribonucleic acid (DNA) and […]
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