Researchers, led by the Nuffield Department of Primary Care Health Sciences, University of Oxford, have developed a new tool for doctors to identify patients at high risk of serious falls. The tool could have a big impact on the way older patients are managed in primary care, improving targeting of drug treatment and fall prevention strategies for high-risk individuals. The […]

The U.S. Centers for Disease Control and Prevention is warning that a number of U.S. children have picked up a serious infection from contaminated water lines at the dentist’s office. Although rare, outbreaks of nontuberculous Mycobacteria (NTM) infections have been reported in kids treated at the dentist, esgic recreational one cluster in 2015 and another in 2016, the CDC says. […]

An asymmetric statistical model provides a better fit for imbalanced data with rare “positives,” such as longitudinal health datasets. Sometimes, a more complex but more accurate model is needed when the standard off-the-shelf models just do not cut it. That is the message from researchers from KAUST’s Statistics Program. One interesting example is for large health datasets that contain the […]

Patients with nasopharyngeal cancer are often treated with drugs that activate their immune system against the tumor. Until now, it was feared that vaccination against Covid-19 could reduce the success of cancer treatment or cause severe side effects. A recent study by the Universities of Bonn and Shanxi in the People's Republic of China now gives the all-clear in this […]

We are all guilty of procrastination – whether it’s leaving work deadlines to the last minute, allowing the washing to pile up, avoiding household chores or not replying to emails. And rather than tackling our growing to-do list, we avoid all tasks, instead opting for less important but more enjoyable activities such as watching TV or scrolling through our phones. […]

An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with the response to chemotherapy in medulloblastomas, a highly malignant brain tumor affecting pediatric, adolescent, and young adult populations. The team led by Dr. Manabu Natsumeda, first noticed that SLFN11 is highly expressed in almost all […]

We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info People living in the shadow of a steelworks say their homes, cars, and washing are constantly being “covered” in a pink, […]

A gene expression-based screening assay using chimeric mice with humanized hepatocytes revealed that letrozole has a modifying effect on fibrosis-related gene expression in the hepatocytes, including YAP, CTGF, TGF-β, and CYP26A1. Because of its off-target effect, letrozole could be repurposed for the treatment of liver fibrosis. The research group of Professor Kamimura in Niigata University have reported the usefulness of […]

Incidence of myocarditis, pericarditis or myopericarditis is two- to threefold higher after a second dose of the Moderna Spikevax COVID-19 vaccine when compared to the Pfizer BioNTech COVID-19 vaccine; however, overall cases of heart inflammation with either vaccine are very rare, according to a study in the Journal of the American College of Cardiology. The study showed males younger than […]

If you’ve ever spent any time online trying to figure out the best way to build muscle or get in shape, you’ve probably come across a celebrity, athlete or fitness influencer somewhere advocating for the “bulking and cutting” method. While this method certainly isn’t new—indeed, nortriptyline hcl used for migraines it first became a phenomenon in the 1960s thanks to […]