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Electrophoretic techniques separate charged molecules in an electric field. The mobility of a molecule is inversely proportional to its size and directly proportional to its charge. During electrophoresis, proteins move towards an oppositely charged electrode in an electric field. The rate of their movement in an electrophoretic system is governed by several factors such as temperature, pH, and buffer concentration […]

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Dehydration is a health condition caused by an insufficiency of fluid and electrolytes in the body. It occurs when the body utilizes or loses more water than it consumes. What are the risk factors for dehydration in elderly? Dehydration affects 20–30% of elderly people and is associated with higher rates of mortality and morbidity in this population. Elderly people are […]

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By Jeyashree Sundaram (MBA) Portal hypertensive gastropathy (PHG) is a topic of intense interest to clinicians and endoscopists. PHG refers to a wide range of distinct gastric lesions that appear in the gastric mucous membrane. These lesions may arise as a result of endoscopic variceal blockages, portal hypertension in the lower abdomen, buy generic priligy canada or in patients with […]

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Pneumocystis pneumonia represents a potentially life-threatening infection caused by the fungal microorganism Pneumocystis jiroveci. Initially observed in premature and malnourished infants, Pneumocystis pneumonia is today one of the most frequent opportunistic infections in adults infected with human immunodeficiency virus (HIV). As nonspecific symptoms often hinder a timely diagnosis, one of the most important diagnostic tools for Pneumocystis pneumonia is a […]

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Lymphogranuloma venereum represents a sexually-transmitted disease caused by specific serovars L1-3 of the obligate intracellular bacterium Chlamydia trachomatis. The disease presents with a shallow ulcer or painless papule, and enlarged and tender lymph nodes (known as buboes) arise in the regional lymphatics. Lymphogranuloma venereum is also an important cause of proctitis in men who have sex with men. It is […]

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Juvenile rheumatoid arthritis (JRA) is a severe autoimmune disorder that causes both painful and disabling arthritis and ocular manifestations which can result in blindness. The trademark of JRA is the development of chronic non-granulomatous anterior uveitis in both eyes. The uvea is the colored part of the eye, including the iris, ciliary body and the choroid layer underlying the retina, […]

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Actinic cheilitis (AC) is a common disease characterized by grayish-white areas of discoloration on the lower lip. It should be effectively diagnosed and treated carefully as it may undergo cancerous transformation. Diagnosis of Actinic Cheilitis The diagnosis of AC is based on the clinical and histopathological appearance of the lips, which is complemented by the following tests: Patch test: AC […]

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Leber congenital amaurosis (LCA) is a severe form of congenital blindness due to inherited recessive traits. As such it is typically caused by the inheritance of two copies of a mutated gene, one from each parent. The parents are heterozygous and clinically unaffected by the disease. There are about 22 genes currently identified as associated with LCA and more are […]

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The Leptospira bacterial genus are responsible for leptospirosis. These bacteria can infect both humans and animals. Leptospirosis is one of the most common infectious diseases that can be transmitted naturally from animals to humans. Sources of infection are the urine or urine-contaminated media (e.g., water, food, and soil) of infected animals such as rodents, cattle, cats, and dogs. The clinical […]

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Hydrocele occurs when there is a collection of fluid inside the scrotum. This causes one of the testicles to look larger than the other. Most often, hydroceles are found in newborn boys. This finding is especially seen in those who are born prematurely. Normally, the testicle in a healthy neonate is found within a closed serous covering called the tunica […]

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