GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

Senescent cells accumulate in organs during aging, promote tissue dysfunction, and cause numerous aging-related diseases like cancer. The cells arise through a process called "cellular senescence," a permanent cell cycle arrest resulting from multiple stresses. A collaborative research group led by Professor Makoto Nakanishi of the Institute of Medical Science, The University of Tokyo (IMSUT), and co-researchers have identified an […]

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SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera

With the coronavirus disease 2019 (COVID-19) pandemic showing no signs of ending soon, the definitive way out is the achievement of population immunity by either vaccination or natural infection. With the unacceptably high mortality rates associated with the latter route, the development of effective vaccines that can induce neutralizing antibodies against the disease’s causative agent – severe acute respiratory syndrome […]

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Survey finds that Asia takes more control of health and retirement amid Covid-19

A year on from Covid-19 first entering the public consciousness, people across Asia are taking more control of their health and retirement planning, as they look to the pandemic’s longer term impact on their personal wealth and lifestyle habits, according to new research from Manulife. The latest version of the “Manulife Asia Care Survey” takes a deep dive look into customers’ concerns, […]

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In pandemic, more people choose to die at home

Mortuary owner Brian Simmons has been making more trips to homes to pick up bodies to be cremated and embalmed since the pandemic hit. With COVID-19 devastating communities in Missouri, his two-person crews regularly arrive at homes in the Springfield area and remove bodies of people who decided to die at home rather than spend their final days in a […]

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Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

A team of scientists from France has recently designed fluorescence in situ hybridization probes (CoronaFISH) to visualize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in infected cells. A detailed description of the probe design, validation, and application is currently available on the bioRxiv* preprint server. Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease […]

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