Could fecal transplants improve melanoma treatment?

Combining fecal transplants with immune checkpoint inhibitors such as pembrolizumab or nivolumab showed the procedure was safe in people with advanced melanoma, according to a phase 1 clinical trial. Of the study participants, 65% responded positively to immunotherapy treatment. Positive responders also showed an increase in beneficial bacteria and a decrease in harmful bacteria in their gut microbiome following the […]

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Seroepidemiology study suggests EV-A71 vaccine effective in Guangzhou, China

Reviewers’ Notes Enterovirus A71 (EV-A71) is a significant hand-foot-mouth disease (HFMD) etiology. The inactivated EV-A71 vaccines were approved in China in 2016. However, the seroprevalence of EV-A71 after the vaccine application and its potential association with the EV-A71 epidemic in the population are rarely studied. The authors of this article analyzed the incidence of EV-A71 infection and seroepidemiology in Guangzhou […]

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Liquid Biopsy Shows Big Promise in Oropharyngeal Cancer

New research supports the use of liquid biopsy as an adjunct biomarker for the diagnosis and surveillance of human papillomavirus (HPV)–associated oropharyngeal cancer. In a retrospective observational cohort study, a commercially available blood test used to evaluate tumor tissue–modified viral-HPV DNA demonstrated 100% specificity for both diagnosis of oropharyngeal cancer and surveillance for recurrence. Sensitivity was 91.5% for correctly identifying […]

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Growing evidence supports prescribing psychostimulants for people at risk of overdose, say researchers

Growing evidence supports prescribing psychostimulant medications to help reduce use of illegal stimulants such as methamphetamine, authors write in a CMAJ (Canadian Medical Association Journal) commentary. Illegal stimulant use is rising, judging by the presence of these drugs in at least half of all opioid deaths in Canada in 2022. Following evidence from clinical trials in Australia, Europe and the […]

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Shoppers Say Their Newborns Are ‘Obsessed’ With This $10 Pack of Rattling Sock Toys That Keeps Them ‘Very Busy'

If you purchase an independently reviewed product or service through a link on our website, SheKnows may receive an affiliate commission. Keeping a newborn entertained is no small feat. By the time you’ve exhausted every silly facial expression you can come up with, your baby might need something new to hold their attention. That’s why we’ve been on the lookout […]

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