Study identifies blood proteins linked to mortality in severe burns

Reviewers’ Notes Researchers led by Osaka University have used mass spectrometry to identify ten blood proteins associated with mortality in severe burns. Three of these proteins (HBA1, TTR, SERPINF2) may serve as targets for developing new treatment methods for burns. Although many people still die from severe burns, the underlying physiology behind burns is not well understood. In an article […]

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Now doctors warn of health impacts of second-hand VAPING

Now doctors warn of health impacts of second-hand VAPING: Study finds e-cigarettes spew out 22-TIMES the safe level of microscopic toxins Levels of potentially toxic chemicals spiked after puffing for just seven minutes The vape plume has typically been believed to be cleaner than cigarette smoke READ MORE:  Sales of vapes soared 50% during pandemic thanks to flavors  Doctors are warning […]

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Four signs when talking that could indicate dementia

Dementia: Expert discusses the signs and symptoms Dementia is a syndrome, which is a group of related symptoms, linked to the ongoing decline of the brain. More typically affecting older people, it can lead to memory loss, behavioural changes and even mobility issues. Although there is no known cure yet for dementia there is treatment and support available out there […]

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BUB1 protein and its kinase activity may regulate EGFR activation

Reviewers’ Notes A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization." EGFR signaling initiates upon ligand binding which leads to activation and internalization of the receptor-ligand complex. In this new study, […]

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Researchers find new genes that contribute to hypoplastic left heart syndrome

Reviewers’ Notes By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome (HLHS), a rare, life-threatening heart disease that occurs in infants. The findings, published in the journal eLife, bring scientists one step closer to unraveling the biology of this complex disease. […]

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Asthma Severity, Exacerbations Increase With RV Infection

TOPLINE: Immunological and quantitative mRNA assays support a pathogenesis role for histamine-releasing factor (HRF), its interaction with HRF-reactive immunoglobulin (Ig)–E and rhinovirus (RV) in asthma severity and exacerbation. METHODOLOGY: Clinical data for healthy controls (HCs) were compared with data from patients with asthma for three distinct cohorts recruited from programs located in Pittsburg, Boston, and Virginia Cohorts differed primarily by […]

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