Therapeutic hypothermia below guidelines did not improve outcomes after cardiac arrest

In patients receiving therapeutic hypothermia after suffering out-of-hospital cardiac arrest, those who were cooled below 31 degrees Celsius (about 88 degrees Fahrenheit) for 24 hours showed no difference in terms of death or poor neurological outcomes at six months compared with patients receiving guideline-recommended cooling of 34 C (about 93 F). These findings are part of a study presented at […]

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HOST-EXAM: Clopidogrel Beats Aspirin as Monotherapy After Stenting

For patients with a drug eluting stent who complete the first 6 to 18 months of dual antiplatelet therapy, continuing with long-term clopidogrel monotherapy was associated with a significantly reduced risk for both ischemic events and major bleeding compared with aspirin monotherapy in the HOST-EXAM randomized trial. Dr Hyo-Soo Kim “These data confirm our working hypothesis that long-term maintenance antiplatelet […]

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Clinical trial suggests convalescent plasma may improve survival with severe COVID-19

A randomized double-blind controlled trial of convalescent plasma for adults hospitalized with severe COVID-19 found that mortality at 28 days in the treatment arm was half the rate seen in the control arm (12.6% vs. 24.6%), although treatment was not associated with other improvements in clinical status. The study was led by investigators from the Center for Infection and Immunity […]

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IBD-Associated Colorectal Cancer Genetically Unrelated to Sporadic Type

NEW YORK (Reuters Health) – Colorectal cancers (CRCs) that evolve from inflammatory bowel disease (IBD) are genetically distinct from sporadic CRC, which may affect prognosis and treatment options, researchers say. “Strikingly, the epithelial tumor subtype most commonly seen in sporadic CRC – consensus molecular subtype (CMS) 2 – was completely absent among IBD-associated tumors,” Dr. Kristiina Rajamäki of the University […]

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Fauci: Encourage, Don’t Require, Vaccinating Children

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. As parents and public health officials consider back-to-school plans for the fall, they should encourage — but not require — COVID-19 vaccination for kids, Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases, said Thursday. “Whenever you’re talking about requiring something, that’s […]

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How Colorado's largest HIE is matching patients with their records

Patient identity matching is a thorny issue: Stakeholders and decision-makers must hammer out a way to link patients to their health information while still taking security, privacy and equity into account.    In Colorado, the largest health information exchange, CORHIO, has teamed up with state agencies to provide identity management services and address that need. By connecting the digital health […]

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