Metformin potently inhibits SARS-CoV-2-induced cytokine release in monocytes

During the ongoing coronavirus disease 2019 (COVID-19) pandemic, it has become clear that hyperactive inflammation is sometimes induced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via its spike antigen. This is mediated by cytokines released by inflammatory cells, such as monocytes. An interesting new bioRxiv* preprint reports the suppression of monocyte glycolysis and cytokine production when exposed to […]
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