Modulating type 1 Interferon may expand treatment options for COVID-19

In their continuing work to limit the impact of COVID-19, Emory University researchers have, for the first time in nonhuman primates, studied how modulating the signaling of type 1 Interferon (IFN-I), one of the body’s initial defenses against infection, impacts SARS-CoV-2 viral replication and disease progression. The findings, which are reported in Science Immunology, demonstrate a critical role of IFN-I […]

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Drug Name Confusion: List of Problem Medications Grows

Zolpidem (Ambien) is a well-known sedative for sleep. Letairis (Ambrisentan) is a vasodilator for the treatment of pulmonary arterial hypertension. Citalopram (Celexa) is an antidepressant; escitalopram (Lexapro) is prescribed for anxiety and depression. Those are just four of the more than 80 pairs of drug names that the Institute for Safe Medication Practices (ISMP) recently added to its list of […]

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Novo boosted as trial shows weight-loss Wegovy drug has medical…

Wegovy reduces the risk of heart attacks and strokes in high-risk patients by a FIFTH, major trial suggests Participants’ risk was reduced by 20 percent, which exceeded expectations   The patients were overweight or obese with a history of heart disease READ MORE: Can Ozempic REALLY cure anxiety and depression?  The blockbuster weight loss drug Wegovy reduces the risk of heart attacks […]

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Physical activity may prevent fatigue in patients with MS

A study led by the University of Eastern Finland found that better physical condition and higher daily activity predicted lower levels of fatigue in patients with relapsing-remitting multiple sclerosis, RRMS. A lower disability rate was also associated with less fatigue. The study was published in the journal Multiple Sclerosis and Related Disorders. Fatigue is one of the most common symptoms […]

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Human antibody that targets carfentanil, fentanyl and related opioids reverses overdose effects in preclinical study

An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research. Carfentanil is a variant of the synthetic opioid fentanyl, and about 100 times as potent as its chemical cousin. Along with fentanyl and other fentanyl variants, it is […]

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