Two mRNA vaccines are effective even without post-shot symptoms or prior SARS-CoV-2 infection

Vaccination with the two messenger RNA (mRNA) vaccines for SARS-CoV-2, the virus that causes COVID-19, yields a robust antibody response, even if a person did not develop significant symptoms following vaccination or did not have a prior SARS-CoV-2 infection. That's the key finding from a recent study of nearly 1,000 health care workers in the Johns Hopkins Health System who […]

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The woman behind the development of mRNA-based vaccines against coronavirus

With her research, biochemist Katalin Karikó laid the foundation for the development of RNA vaccines against the coronavirus. Now she is being honoured for this by the Würzburg Societas Physico-Medica. She is "the woman behind the vaccine breakthrough", as Euronews writes. She made "a discovery that now seems worthy of a Nobel Prize to many experts", according to the Süddeutsche […]

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Wake Forest and AFAR receive up to $5 million NIA renewal award to continue management of RCCN

Wake Forest School of Medicine and the American Federation for Aging Research (AFAR) have received a renewal award for up to $5 million over five years from the National Institute on Aging (NIA), National Institutes of Health, to continue their management of the Research Centers Collaborative Network (RCCN). The RCCN brings together scientists from six NIA center programs focused on […]

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How To Know If You’re Addicted To Caffeine

Bangkok Click Studio/Shutterstock By Raegan Davies/Aug. 25, 2021 4:40 pm EDT It’s on mugs, tee shirts, even your aunt’s Facebook status — “don’t talk to me before I’ve had my coffee.” Most of us have felt like this at some point, whether we use our morning cup of coffee as a time to relax before starting our morning or as a […]

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Team unveils widespread tumor suppression mechanism that stops cancer progression by interfering with cell metabolism

According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth. These findings, published today in Science Advances, demonstrate that metabolic and mitochondrial reprogramming, which are well-established hallmarks of tumor progression, […]

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Llama Antibodies Blunt COVID Variants in Lab Trial, Says Belgian Start-Up

GHENT, Belgium (Reuters) – Llama antibodies could soon be playing a role in the global fight against COVID-19, if clinical trials being conducted by a Belgian biomedical start-up live up to their early promise. Researchers from the VIB-UGent Center for Medical Biotechnology in Ghent say antibodies extracted from a llama called Winter have blunted the virulence of coronavirus infections, including […]

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Psoriatic arthritis worsens quality of life in patients with psoriasis

(HealthDay)—People with psoriasis/psoriatic arthritis (PsA) have a decreased ability to participate in social roles and activities and more depressive symptoms than those with psoriasis alone, according to a research letter published online July 21 in the British Journal of Dermatology. George C. Gondo, from the National Psoriasis Foundation in Portland, Oregon, and colleagues surveyed 1,570 individuals with psoriatic disease to […]

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Unconventional T cell and inflammation levels in COVID-19 during pregnancy

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in 2019 in Wuhan, China. The rapid spread of this virus worldwide led to the coronavirus disease 2019 (COVID-19) pandemic that has claimed more than 4.45 million lives worldwide. It is essential to understand the immune responses to SARS-CoV-2 to develop better therapeutics and vaccines. Study: Integrated immune networks […]

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