New Trials in Prostate Cancer: Could Your Patient Benefit?

Several new clinical trials in prostate cancer have opened in recent months. Maybe one of your patients is eligible to participate? Prostate cancer at high risk for biochemical recurrence following radical prostatectomy and/or radiation therapy. Adult patients with this diagnosis can join a randomized, double-blind, placebo-controlled phase 3 study evaluating darolutamide (Nubeqa) plus androgen deprivation therapy (ADT) against ADT alone. […]

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Ketogenic diets, gut microbiota, and health effects

In a recent study published in the Nutrients Journal, researchers summarized the evidence on ketogenic diets (KDs) from the past three decades. ​​​​​​​Study: The Influence of Ketogenic Diet on Gut Microbiota: Potential Benefits, Risks and Indications. Image Credit: Boontoom Sae-Kor/Shutterstock.com Background KD is characterized by minimal intake of carbohydrates, low calories, standard protein levels, and high fat intake. This dietary approach induces […]

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Researchers discover novel approach for rebuilding, regenerating lung cells

Researchers from the Center for Regenerative Medicine (CReM), a joint venture between Boston University and Boston Medical Center, have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describing the methodologies for engineering lung stem cells […]

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Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

In a recent study posted to the medRxiv* preprint server, a group of researchers identified large deletions in individuals with unexplained hyperinsulinism (HI), thereby elucidating the potential dysregulation of Forkhead box protein A2 (FOXA2) expression and its implications for syndromic HI. Study: Chromosome 20p11.2 deletions cause congenital hyperinsulinism via the likely disruption of FOXA2. Image Credit: angellodeco/Shutterstock.com *Important notice: medRxiv publishes preliminary scientific reports […]

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Firearm injuries and the pandemic: Lower opportunity neighborhoods disproportionately affected

During a time when hospitals were overrun with COVID-19 patients and ventilators were in high demand, the nation’s focus was not on firearm-related injuries. With our attention elsewhere, it may have seemed that these injuries appeared to decrease and mass shootings seemed to disappear. But that doesn’t mean firearm injuries went away. In fact, for one group of children in […]

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Acne bacteria trigger cells to produce fats, oils and other lipids essential to skin health, shows new research

The skin is the largest organ of the body, and it plays a crucial role as the first line of defense against pathogens and insults from the external environment. It provides important functions like temperature regulation and moisture retention. And despite the misconception that lipids harm your skin by causing oiliness and acne, they actually play a vital role in […]

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