Association between SARS-CoV-2 infections and areal level deprivation and ethnicity in England

Coronavirus disease 2019 (COVID-19) is undoubtedly a disease of minorities and underprivileged people, judging from the disproportionately high rates of cases and deaths in this population. A new study from the UK shows that, in agreement with other studies, the presence of inequality favors a heavier impact and that this showed dynamic changes as policies changed and newer virus variants […]

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Solid-tumor cancer patients ineligible for clinical trials receive more immunotherapy but may not benefit

Cancer patients who are ineligible for clinical trials receive immune checkpoint inhibitors (ICI) at greater rates than patients who are trial eligible despite no survival benefit, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania. The study, published in JAMA Oncology, suggests that the positive results for phase 3 clinical trial […]

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Study encourages cautious approach to CRISPR therapeutics

A comprehensive study—conducted by researchers at Sanford Burnham Prebys, the National Cancer Institute (NCI) and other groups—has shown that gene editing, specifically gene knockout (KO), with CRISPR -Cas9 can favor cells with mutated forms of genes linked to cancer. The findings highlight the need to monitor patients undergoing CRISPR-Cas9-based gene therapy for cancer-related mutations. The study was published in the […]

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Prescription drug for multiple sclerosis improves memory in Alzheimer's mouse model

Losing memory is a hallmark of Alzheimer's, a symptom of the disease that depletes a patient's quality of life. Improving memory and slowing cognitive changes caused by the disease is an ongoing challenge for researchers seeking to develop novel therapies. In a newly published paper in Frontiers in Neuroscience, researchers at the Del Monte Institute for Neuroscience at the University […]

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COVID-19 vaccine: How was it developed so fast?

Since the beginning of the pandemic, healthcare workers have administered billions of COVID-19 vaccine doses. In this Special Feature, we speak with medical experts about how scientists made coronavirus vaccines so rapidly without compromising safety. SARS-CoV-2, the virus that causes COVID-19, was first identified in December 2019. By December 11, 2020, the Pfizer vaccine became the first to receive emergency […]

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App-based protocol identifies delirium in hospitalized adults

(HealthDay)—An app-directed protocol is feasible, brief, and accurate for diagnosing delirium among inpatients, according to a study published online Nov. 9 in the Annals of Internal Medicine. Edward R. Marcantonio, M.D., from Harvard Medical School in Boston, and colleagues tested implementation of a brief app-directed protocol in real-world practice compared with a research reference standard delirium assessment (RSDA). Participants included […]

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Vitamin D deficiency symptoms: Most common signs of a deficiency that aren’t ‘obvious’

Vitamin D: Sarah Jarvis discusses use in combatting COVID-19 We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Vitamin D is absolutely crucial for the body’s overall wellbeing and […]

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