Genetic-code expansion technique to potentially create next-generation vaccine candidate

Most viral infections are difficult to control and are caused by ribonucleic acid (RNA) viruses. Viral-engineering methods could be adapted to effective and smart vaccine design by integrating advances in reverse genetics with insights from system vaccinology. Study: Engineering RNA viruses with unnatural amino acid to evoke adjustable immune response in mice. Image Credit: deepadesigns/Shutterstock A replication-incompetent virus that propagates […]

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The power of learning from experience

In a first study, researchers from the Max Planck Institute for Human Development and the University of the Balearic Islands analyzed the development of research on statistical reasoning from a historical perspective. In the 1960s, adults were still considered to be good intuitive statisticians. From the 1970s, however, this notion was overturned. Since then, studies on so-called “heuristics and biases” […]

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“I did 5 minutes of pilates every day for 2 weeks and saw some surprising results”

Five minutes a day might not seem long enough to do any genuine exercise but after spending two weeks doing five-minute pilates workouts, writer Sakshi Udavant says that she’s never been stronger. If you’re anything like me, you’ll have found yourself increasingly short on both time and new ideas – particularly when it comes to working out. For ages, I’ve […]

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What Teen Girls Wish Parents Knew About Instagram

Many parents don’t need to read Meta’s internal research to know that Instagram can be toxic for teens, especially those who identify as female in that they may trigger depression or body-image issues. Following a September Wall Street Journal article that revealed Meta (formerly known as Facebook and the parent company of Instagram) was aware of Instagram’s negative impact on […]

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Development and effectiveness of pseudotyped SARS-CoV-2 system

Coronavirus disease 2019 (COVID-19) has become a global pandemic. Currently, SARS-CoV-2 live virus-associated experiments need to be handled in biosafety level 3 (BSL-3) facilities. Previously, researchers had successfully established an HIV-based, pseudotyped virus system for studies on MERS-CoV and Ebola virus. Using the pseudotyped virus system, viral entry associated research, e.g., neutralization assays and in vitro pharmacodynamics, can thus be […]

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Proactive wins over reactive responses to COVID-19

At the beginning of the coronavirus disease 2019 (COVID-19) pandemic, a number of non-pharmaceutical interventions (NPIs) were introduced to help reduce the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While these measures did completely mitigate the size of the outbreak, they imposed a significant load on social, economic, and educational systems that caused suffering worldwide. A new […]

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Computer-, smartphone-based treatments effective at reducing symptoms of depression

Computer- and smartphone-based treatments appear to be effective in reducing symptoms of depression, and while it remains unclear whether they are as effective as face-to-face psychotherapy, they offer a promising alternative to address the growing mental health needs spawned by the COVID-19 pandemic, according to research published by the American Psychological Association. “The year 2020 marked 30 years since the […]

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New COVID-19 antibody drug OK’d to protect most vulnerable

Federal health officials on Wednesday authorized a new COVID-19 antibody drug for people with serious health problems or allergies who can’t get adequate protection from vaccination. Antibody drugs have been a standard treatment for treating COVID-19 infections for over a year. But the AstraZeneca antibody drug cleared by the Food and Drug Administration is different. It’s the first intended for […]

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