Findings from a new study led by Yale Cancer Center show the small molecule inhibitor drug, PF05175157, originally developed to treat diabetes by Pfizer, may help in the treatment of breast cancer. The findings were reported today at the 2021 San Antonio Breast Cancer Symposium in San Antonio, Texas. Our research shows the preclinical, anti-cancer activity using PF05175157 may lead […]

People who exercise regularly can reduce their risk of developing and dying from pneumonia, new research has found. The study, led by the University of Bristol and published in GeroScience, analyzed, for the first time, ten population cohort studies with over one million participants. The benefits of regular exercise are well-known and can reduce the risk, length or severity of […]

Statins: How the drug prevents heart attacks and strokes We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info The National Institute for Health and Care Excellence has advocated for […]

Different institutions, including the University of Valencia (UV), have studied the relationship between sarcopenia (loss of muscle mass in older people) and obesity derived from this condition with a lack of protein in the diet of women over 65 years of age. 164 Valencian women participated in the study, published in the journal Nutrición Hospitalaria. “The approach of sarcopenia has […]

Elaine Duryea, M.D., Assistant Professor in the Department of Obstetrics and Gynecology. Credit: UT Southwestern Medical Center Researchers at UT Southwestern Medical Center studied outcomes for young women at a county hospital and found that while 97% of them accessed prenatal care, those with greater social needs were associated with adverse outcomes both during pregnancy and during the early weeks […]

Researchers have linked a rare genetic mutation found mostly in Black Americans and other people of African descent to an earlier onset of heart failure and a higher risk of hospitalization. The findings suggest that earlier screening for the mutation could lead to faster treatment and improved outcomes for heart failure in this vulnerable group, the researchers said. The results […]

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative virus of coronavirus disease 2019 (COVID19).. Effective preventive strategies were scarce, particularly at the start of the pandemic. Even by late 2021, only 56.5% of the world's population will have been vaccinated, and some will not respond. The importance of effective prevention is greatest in households with SARS-CoV-2 infected people […]

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Working feverishly to complete the myriad patient notes accumulated throughout a hectic day, my phone vibrated – alerting me to a number that, over the past several years, has wrought uncertainty, grief, and overwhelming relief. Answering hesitantly, I listened to my physician’s pharmacist inform me of […]

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists. The scientists, from the National Eye Institute (NEI), part of the National Institutes of Health, published their findings today in Nature Communications. “This stem-cell-derived model of dry AMD is a game-changer. Scientists […]

Scientists at the Francis Crick Institute, in collaboration with University of Kent, have used gene editing technology to create female-only and male-only mice litters with 100% efficiency. This proof of principle study, published in Nature Communications today (Friday 3rd December), demonstrates how the technology could be used to improve animal welfare in scientific research and perhaps also agriculture. In scientific […]