Target identified to improve immunotherapy against solid tumors: Transcription factor Blimp1

In cancer, a major obstacle to anti-tumor immunity and immunotherapy treatment is the infiltration of regulatory T cells, or T-reg cells, into a tumor. These immune cells generally turn down the immune response, and they can prevent the immune system from destroying cancer cells. University of Alabama at Birmingham researcher Jianmei Leavenworth, M.D., Ph.D., has now identified the transcription factor […]

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Over 4 million doses of University of Oxford-AstraZeneca vaccine donated by UK to Bangladesh

The UK donated over 4 million doses of the University of Oxford-AstraZeneca vaccine, made by Oxford Bio-medica in Oxford and packaged in Wrexham, North Wales, to Bangladesh through the COVAX vaccine sharing mechanism. Bangladesh's fight against the coronavirus pandemic, and the country's economic recovery, will be reinforced by this donation from the UK.The vaccine consignment arrived in Bangladesh on 13 […]

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New allocation model to optimize the distribution of COVID-19 vaccines, treatments

Lulu Kang, associate professor of applied mathematics at Illinois Institute of Technology and a team of researchers from the University of Illinois Chicago put a new twist on traditional resource allocation models to optimize the distribution of COVID-19 vaccines, treatments, testing supplies, and other related resources, publishing their findings, "Fair and Diverse Allocation of Scarce Resources," in Socio-Economic Planning Sciences. […]

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Scientists detect COVID-19 infection in white-tailed deer in 6 Ohio locations

Scientists have detected infection by at least three variants of the virus that causes COVID-19 in free-ranging white-tailed deer in six northeast Ohio locations, the research team has reported. Previous research led by the U.S. Department of Agriculture had shown evidence of antibodies in wild deer. This study, published today (Dec. 23, 2021) in Nature, details the first report of […]

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Gum disease increases risk of other illness such as mental health and heart conditions, study finds

A University of Birmingham-led study shows an increased risk of patients developing illnesses including mental ill-health and heart conditions if they have a GP-inputted medical history of periodontal (gum) disease. Experts carried out a first of its kind study of the GP records of 64,379 patients who had a GP-inputted recorded history of periodontal disease, including gingivitis and periodontitis (the […]

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RSV Resurgence Likely in Wake of COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The impact of respiratory syncytial virus (RSV)will likely be greater in 2021 and 2022 in the United States than in previous years as a result of the ongoing COVID-19 pandemic, based on data from a simulation-modeling study involving approximately 19 million individuals. Although RSV usually follows […]

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California State University to require COVID-19 boosters

California State University, the nation’s largest four-year-public university, said Wednesday that it will require students, faculty and staff at its 23 campuses to get COVID-19 booster shots for the spring semester amid concerns about the highly contagious omicron variant. The mandate, which allows for medical and religious exemptions, requires the boosters by Feb. 28, or six months after the final […]

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Proactive Infliximab Monitoring Best Sustains Disease Control

A new study has found that proactive therapeutic drug monitoring (TDM) with maintenance infliximab is more effective than standard therapy in sustaining control of immune-mediated inflammatory diseases. The findings from the trial, published December 21 in JAMA, called Norwegian Drug Monitoring B (NOR-DRUM B), provide greater support to the usefulness of TDM in proactively monitoring serum drug levels and antidrug […]

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