Pre-Omicron COVID-19 Transmission 3x Higher Among Unvaccinated

NEW YORK (Reuters Health) – People with breakthrough cases of COVID-19 earlier this year were much less likely than unvaccinated COVID-19 patients to infect others, a population-based study from Germany shows. The findings are based on data collected until August 2021, before the Omicron variant emerged. “The number of transmissions from unvaccinated controls was three times higher than from fully […]

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Oral JAK Inhibitor Continues to Show Promise for Alopecia Areata

NEW YORK (Reuters Health) – Treatment with the investigational oral Janus kinase (JAK) inhibitors ritlecitinib or brepocitinib led to molecular and clinical improvement in scalp lesions in patients with alopecia areata enrolled in a biopsy sub-study of the phase-2 ALLEGRO trial. “Alopecia areata is a chronic, relapsing autoimmune disorder with an approximate 2% lifetime incidence among patients in the United […]

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Video: Recognizing ‘holiday heart’

“Holiday heart” may sound like another joyous part of the holiday season. “But, in the cardiology world, ‘holiday heart’ actually refers to this effect of the stress of too much alcohol, too much salt, higher blood pressure on the heart,” says Dr. Amy Pollak, a Mayo Clinic cardiologist. Dr. Pollak says all that stress on the heart can cause an […]

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Heterologous COVID Booster: No Better Response in Kidney Patients

(Reuters Health) – Kidney transplant recipients have similar outcomes with both heterologous and homologous third SARS-Cov-2 vaccine doses, a randomized clinical trial suggests. For the trial, researchers randomized 197 kidney transplant patients who didn’t have antibodies against the SARS-Cov-2 spike protein after two doses of a mRNA vaccine from Moderna or Pfizer/BioNTech. Patients were randomized 1:1 to receive either a […]

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Orphanhood decreases with the availability of antiretroviral therapy and male circumcision

Researchers at Columbia University Mailman School of Public Health found marked decreases in orphanhood particularly double orphanhood, among adolescents in Rakai, Uganda, corresponding with the availability of antiretroviral therapy (ART) beginning in 2004 and of male medical circumcision in 2007. Until now, little had been known about the contribution of HIV combination prevention including ART and male circumcision to recent […]

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