New data suggest machine learning algorithms can accurately predict C. diff infection in hospitalized patients

New data published today suggest that several commonly used machine learning algorithms (MLAs) can effectively predict which hospitalized patients will become infected with Clostridiodes difficile (C. diff). The findings, which appear in the American Journal of Infection Control (AJIC), the journal of the Association for Professionals in Infection Control and Epidemiology (APIC), could support infection prevention and early diagnosis, as […]

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Antibiotic-resistant superbugs killed 1.2MILLION people in 2019

Antibiotic-resistant superbugs killed 1.2MILLION people in 2019 — more than HIV or malaria, major study finds Antibiotic resistant  bacteria have killed 1.2million people in 2019, according to a new US and UK lead study The ‘superbugs’ were also estimated to have contributed to the deaths of almost 5million people globally Bacteria which have grown resistant to medication are considered to be […]

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Repeat CT: Unraveling Plaque Changes in CAD With Elevated Lp(a)

New research suggests serial coronary CT angiography (CCTA) can provide novel insights into the association between lipoprotein(a) and plaque progression over time in patients with advanced coronary artery disease. Researchers examined data from 191 individuals with multivessel coronary disease receiving preventive statin (95%) and antiplatelet (100%) therapy in the single-center Scottish DIAMOND trial, and compared CCTA at baseline and 12 […]

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Cardiac Function Normalizes by 3 Months in MIS-C in Study

Most children with multisystem inflammatory syndrome related to COVID-19 infection show recovery of cardiac function by 3 months, but longer term follow-up is still needed, suggests a new retrospective longitudinal cohort study. While 80%-85% of children with multisystem inflammatory syndrome have cardiovascular involvement, “lack of knowledge about the short-term consequences of MIS-C has led to uncertainty among physicians in making […]

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Review reports improved transparency in antidepressant drug trials

New research suggests manufacturers of newly developed antidepressant drugs have become more forthcoming about clinical trials that don’t pan out. A new review and meta-analysis, published today in the journal PLOS Medicine, indicates that drug companies conducting clinical trials on new antidepressants have increased disclosure of clinical trials with negative outcomes, that is, trials that fail to show the drug […]

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Appendectomy or Antibiotics? Large Trial Helps Decision Making

A new analysis of data from a major US trial comparing antibiotics to surgery for appendicitis yielded more information that can help patients weigh options for treatment. The presence of mineralized stool, known as appendicolith, was associated with a nearly twofold increased risk of undergoing appendectomy within 30 days of initiating antibiotics, write David Flum, MD, of the University of […]

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