Successfully operationalizing population health

Population health has been a healthcare industry buzzword for over ten years now and organizations have sought to try to transform their structure and organization to achieve the promise of population health.  While some have been successful, others have not. Jonas Varnum, Vice President of Population Health at Health Catalyst, discusses how to successfully operationalize population health and missteps to […]

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Developing post-vaccination SARS-CoV-2 standard reference sera

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as other ribonucleic acid (RNA) viruses, harbors error-prone polymerases that endure frequent genome mutation. This leads to the generation of diverse genomes and multiple viral quasispecies among individuals. Study: Establishment of human post-vaccination SARS-CoV-2 standard reference sera. Image Credit: Victor Moussa / Shutterstock.com Background Viral mutations have led to an […]

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Young cannabis addicts at higher risk of repeated strokes, study finds

Stroke survivors are 50% more likely to suffer another if they are heavy cannabis smokers, study finds US study found cannabis addicts have higher chance of having repeated strokes Doctors looked at health data collected from 160,000 patients across the US Researchers have called for more warning to young people about cannabis use  Cannabis addicts who survive a stoke are nearly […]

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Midlife chronic conditions linked to increased dementia risk later in life

Having two or more chronic conditions (known as multimorbidity) in middle age is associated with an increased risk of dementia later in life, finds a large study of British adults, published by The BMJ today. Common chronic conditions include high blood pressure, diabetes, coronary heart disease, depression, and chronic lung disease (COPD). The results show that the risk is greater […]

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COVID Risk Factors in Multiple Sclerosis Identified

A younger age, the presence of comorbidities, and female sex are all factors associated with an increased risk for COVID-19 in patients with multiple sclerosis (MS), new research suggests. In a case-control study that included 2337 patients with MS, the odds ratio (OR) for risk for COVID-19 infection among patients with comorbidities was 1.69 vs those without comorbidities. The researchers […]

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Black and Latinx men are under-represented in online prostate cancer resources

Despite their higher risks of advanced prostate cancer, Black and Latinx men are under-represented on websites and in online videos providing information and education regarding prostate cancer, reports a study in the Journal of Urology. “Online media have significant potential for public education and combating health disparities,” comments lead author Stacy Loeb, MD, MSc, Ph.D. (Hon), of New York University Langone […]

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SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

A team of researchers used co-immunoprecipitation (co-IP) and in vitro interaction assays to identify the molecular basis of interaction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 2 (NSP2) with eIF4E-homologous protein (4EHP)-GRB10-interacting glycine-tyrosine-phenylalanine domain protein 2 (GIGYF2) complex, involved in microRNA(miRNA)-mediated gene silencing in human cells. The study can be found on the bioRxiv* preprint server before […]

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