Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an interdisciplinary team of researchers from the United Kingdom (UK) and Switzerland elucidated antiviral activities of aminoglycoside geneticin against seven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants using different cell lines and respiratory tissues. Study: Geneticin shows selective antiviral activity against SARS-CoV-2 by targeting programmed -1 ribosomal frameshifting. Image […]

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New modeling framework developed to improve infectious disease control

A new model to analyze infectious disease outbreak data has been developed by mathematicians that could be used to improve disease tracking and control. Researchers from the University of Nottingham developed a new data-driven framework for modeling how infectious diseases spread through a population that could reduce errors in decisions made about disease control measures. Their findings have been published […]

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Valneva wins first COVID-19 vaccine approval

French-Austrian biotech firm Valneva on Tuesday said its COVID-19 vaccine received emergency authorisation for use in Bahrain, the first approval for its jab. Valneva committed to supplying the Gulf kingdom with one million doses in an advance purchase agreement last year and plans to deliver the first batches at the end of March. The jab, which uses the traditional technology […]

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Patients with inflammatory skin diseases have high stress scores

About two-thirds of patients with inflammatory skin diseases have high reported stress scores, according to a letter to the editor published online Feb. 19 in the Journal of the European Academy of Dermatology and Venereology. Laurent Misery, M.D., Ph.D., from the University of Brest in France, and colleagues conducted an observational, cross-sectional, noncomparative study between October 2020 and February 2021 […]

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Global COVID-19 Death Toll Surpasses 6 Million

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The official global COVID-19 death toll passed 6 million on Monday, marking another grim milestone as the pandemic enters its third year. The U.S. has reported the highest number of deaths by far, with more than 958,000 total deaths as of Monday morning, according to the […]

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On preparing for the next pandemic now

Aled Edwards is of two minds about medicine’s response to COVID-19. On one hand, he notes, we had life-saving vaccines and therapies less than a year after the discovery of SARS-CoV-2. On the other, more than six million, and possibly as many as 18 million people have died, and global access to advances that can prevent and treat severe disease […]

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Could psychedelics revolutionise the way we treat anxiety and depression?

After decades of association with hippy culture, psychedelics could be the answer to treating growing rates of depression and anxiety. Psilocybin is the naturally-occurring active ingredient in psychoactive or “magic” mushrooms. Dr. Alana Roy is a psychologist, academic and Psychological Services Practice Manager at Melbourne’s Mind Medicine Institute. She says psilocybin shows promising results when used in psychedelic-assisted psychotherapy. “The […]

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A new method to produce complex natural products in amoebae

A research team at the Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (Leibniz-HKI) in Jena, Germany has developed a new method to produce complex natural products in amoebae. These polyketides include various antibiotics but also olivetolic acid, a precursor of the herbal active ingredient tetrahydrocannabinol (THC). The results were published in Nature Biotechnology. Polyketides […]

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