Exploring the drivers of Catatonia and Acute Regression in Down Syndrome

When clinical psychiatrist and University of Queensland researcher Dr Cathy Franklin saw her first patient with Catatonia and Acute Regression in Down Syndrome in 2009, she was shocked. The condition strikes young people with Down Syndrome, who might previously have been active and high functioning, causing them to suddenly regress. These young people can go from being able to talk, […]

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Depression and Dry Eye Correlation Probed

Symptoms of dry eye correlated with depression in one of the largest studies to examine the relationship. Clinicians should take the relationship into consideration when treating either condition, said Gui-shuang Ying, PhD, a professor of ophthalmology at the University of Pennsylvania in Philadelphia. “I would say that if the patient sees a doctor for dry eye, the doctor should check […]

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Two drugs show promise in rejuvenating lung epithelial progenitor cells damaged by COPD

A team of researchers from the Netherlands, Germany and the U.S. reports that two drugs show promise in rejuvenating lung epithelial progenitor cells damaged by chronic obstructive pulmonary disease (COPD). In their study, published in the journal Science Advances, the group identified certain proteins involved in epithelial generation for targeting with prostanoids and tested them under different scenarios. Sean Fortier, […]

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Study finds lesser number of female principal investigators in cardiovascular clinical trials

Despite recent efforts to improve women's leadership in cardiovascular clinical trial research over the last decade, the number of female principal investigators (PIs) still falls well below the number of males leading similar heart studies, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session. I was rather surprised that despite efforts to improve female […]

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Evolution of brain tumor classification

For more than a century, pathologists have classified and graded brain tumors, examining samples under a microscope and looking for telltale signs of tumor class and biological aggressiveness such as cell morphology, cell death, new blood vessels and cell proliferation. However, the advent of more affordable genetic sequencing and the discoveries from large studies such as The Cancer Genome Atlas […]

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Maternal and infant antibody levels and transplacental transfer following SARS-CoV-2 infection and vaccination

A recent study posted to the medRxiv* preprint server evaluated maternal antibody responses against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and transplacental transfer. Study: Maternal Antibody Response and Transplacental Transfer Following SARS-CoV-2 Infection or Vaccination in Pregnancy. Image Credit: Margarita Fink/Shutterstock Background Growing evidence suggests that pregnant women are at an increased risk of severe coronavirus disease 2019 (COVID-19), requiring […]

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