Genetic screening of refractory tumors benefits young cancer patients

Cancer therapies targeting specific genetic mutations may offer benefits to patients for whom other standard chemotherapy treatments have not effectively treated their tumor. However, genetic screening of tumors is not routinely performed for pediatric and young adult cancer patients. To increase access to tumor genetic screening and study the utility of this strategy, the National Cancer Institute (NCI), part of […]

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Study finds antimicrobial resistance is making UTIs more deadly

Antimicrobial resistance (AMR) occurs when bacteria and other microbes become resistant to the drugs designed to kill them, generally through misuse or overuse of the drugs. There are two ways resistant bacteria can be passed between humans: hospital transmission and community transmission. Hospital acquired resistance is well researched, but this study is one of the few that looks at the […]

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Exercise improves health markers in young female survivors of childhood trauma

New research shows a progressive exercise training program mitigates some physiological and psychological effects of adverse childhood experiences (ACE) in otherwise healthy young women. These experiences are linked to “lasting, negative effects on health, well-being, as well as life opportunities,” according to the U.S. Centers for Disease Control and Prevention. The study will be presented this week at the American […]

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Can weekly prednisone treat obesity?

Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight, reports a new Northwestern Medicine study. The mice also had increased muscle metabolism. The once-weekly prednisone promoted nutrient uptake into the muscles. Investigators also found these mice had increased adiponectin […]

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Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

A recent study published in PLOS ONE analyzed the polymorphisms in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) proteins' S1/S2 subunits.  Study: Functional analysis of polymorphisms at the S1/S2 site of SARS-CoV-2 spike protein. Image Credit: Design_Cells/Shutterstock Background The SARS-CoV-2's S protein mediates the host entry of the virus. The S protein interacts with the host angiotensin-converting […]

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Vaccine protects most cancer patients from COVID, but risk remains higher for patients with blood cancers

Using the nation’s largest COVID-19 data resource, a researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center found the COVID-19 vaccine protected most cancer patients from getting COVID. However, patients with certain types of cancer have a higher and widely varied risk of breakthrough COVID infections after receiving the COVID vaccine. Jing Su, Ph.D., assistant professor in […]

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