Scientists show how T cells may help protect against severe COVID

In a recent study published in the Clinical Infectious Diseases journal, the researchers summarized the perspectives and observations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related adaptive immunity.   Various studies have reported the association of T-cell responses with mild coronavirus disease 2019 (COVID-19) disease outcomes. Furthermore, it has been reported that preexisting cross-reactive immunity can lower COVID-19 disease severity. Study: […]

Continue reading »

Researchers develop IV injection treatment for sepsis

Purdue University researchers in the College of Pharmacy and College of Engineering are developing a patent-pending treatment that could impact millions of American lives each year. The Centers for Disease Control and Prevention reports that at least 1.7 million American adults develop sepsis annually; almost 270,000 die as a result. One in three patients who die in a hospital has sepsis. […]

Continue reading »

Drug interaction checkers could have caught adverse events

Use of drug interaction checkers could have identified several drug-drug interaction (DDI)-associated adverse drug reactions, including severe and life-threatening events among patients with COVID-19, according to a review published online April 19 in JAMA Network Open. Valeria Conti, Ph.D., from University of Salerno in Italy, and colleagues conducted a systematic literature review to identify DDIs that led to adverse clinical […]

Continue reading »

Palmitoylation, a new target for anti-cancer drugs

Peripheral membrane proteins temporarily bind to cell membranes, a necessary step for them to be able to fulfill their biological function. To do this, certain enzymes that catalyze their lipid modification come into action. This process is called palmitoylation. Some of these proteins can mutate and become oncogenic, such as the RAS proteins, which are responsible for about one third […]

Continue reading »

Within-host model for the description of SARS-CoV-2 viral dynamics in the upper respiratory tract

A team of UK-based scientists has recently developed a within-host model to determine the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the upper respiratory tract of affected individuals. The study finds that infected individuals can transmit the disease for up to 8 days. However, the virus can be detected in their body for up to 27 […]

Continue reading »
1 473 474 475 476 477 1,322