Ruth Langsford says husband Eamonn makes her feel ‘sexy’ We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info The conversation concerning menopause was not the first time the presenter […]

You can find a post, paper or article online to support just about whichever diet or eating ideology you subscribe to. No wonder it’s all so bloody confusing – even Dr Rupy from The Doctor’s Kitchen finds it tough. Anyone who’s ever looked for the answer to a nutrition or diet question online will know that the digital space is packed […]

Rhabdomyosarcoma is a type of soft tissue cancer. Scientists at St. Jude Children’s Research Hospital studied the population of cells that persists after therapy, causing rhabdomyosarcoma recurrence. They found that these cells mirror an early developmental state that responds to EGFR inhibitors. The work presents a strategy for targeting the whole tumor that may apply to other pediatric cancers. The […]

In a recent study posted to the medRxiv* preprint server, researchers assessed the antibody responses elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and defined the epitopes shared by them. Several SARS-CoV-2 variants of concern have emerged since the beginning of the coronavirus diseases 2019 (COVID-19) pandemic. These variants differ from each other in characteristics, including transmissibility and […]

Researchers at Baylor College of Medicine and collaborating institutions have identified a combination therapy for treating triple-negative breast cancer (TNBC) that results in durable tumor regression in an animal model of the condition. The combination therapy attacked the tumor on two fronts. On one side, the chemotherapy drug cyclophosphamide eliminated tumor cells, while on the other front, another drug inhibited […]

Roughly a third of all drugs approved by the U.S. Food and Drug Administration target a large family of biomolecules, known as G protein-coupled receptors (GPCRs), whose job is to trigger cellular responses to extracellular stimuli. More than 800 different kinds of GPCRs exist in the human body and play a role in the pathobiology and treatment of countless medical […]

Upper airway hypoglossal nerve stimulation is safe and effective in adolescents with Down syndrome and severe persistent obstructive sleep apnea (OSA) occurring after adenotonsillectomy, and who couldn’t tolerate positive airway pressure, early research suggests. In a phase I study, 42 adolescents received a surgically implanted device that moves the tongue forward during sleep. Results at 1-year follow-up showed 66% “responded […]

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context. A major challenge for researchers has been how to model body functions and systemic diseases with multiple engineered tissues that can physiologically communicate—just like they do in the body. However, it is essential to provide each engineered tissue […]

Differential item functioning (DIF) is minimal across race and sex in the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), according to a study published online April 26 in JAMA Network Open. Luther G. Kalb, Ph.D., from the Kennedy Krieger Institute in Baltimore, and colleagues conducted a cross-sectional study of children who were evaluated for autism spectrum disorder between 2014 and […]

A Florida court recently overturned mask mandates on planes in the United States, saying the directive was unlawful. That decision is now under appeal. Before that, Australian comedian Celeste Barbertold her social media followers a passenger sitting next to her on a recent flight took off her mask to sneeze. So wearing masks on planes to limit the spread of […]