Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women
In a recent article published in Nature Medicine, researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 (PNPLA3) p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease (FLD) while a rapidly progressive disease ensues in some peri- and postmenopausal women. Study: Interaction between estrogen receptor-α […]
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