New "masked" version of immunotherapy could help fight cancer without causing side effects

Many cancer treatments are notoriously savage on the body; they attack healthy cells at the same time as tumor cells, causing a plethora of side effects. Now, researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) have designed a method to keep one promising cancer drug from wreaking such havoc. The team has engineered a new "masked" […]

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Antibiotics wreak havoc on athletic performance: Knocking out gut bacteria deflates the will, ability to exercise

New research demonstrates that by killing essential gut bacteria, antibiotics ravage athletes’ motivation and endurance. The UC Riverside-led mouse study suggests the microbiome is a big factor separating athletes from couch potatoes. Other studies have examined the way that exercise affects the microbiome, but this study is one of few to examine the reverse — how gut bacteria also impact […]

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Sex-Adjusted Liver Allocation Scoring Tool Would Improve Transplant Equity

NEW YORK (Reuters Health) – Females on the liver transplant waiting list are disadvantaged by the sodium-adjusted Model for End-stage Liver Disease score (MELDNa) currently employed to guide allocation decisions, but a sex-adjusted MELDNa score would help address the inequity and decrease mortality for both sexes, researchers say. Dr. Julia Sealock of Vanderbilt University Medical Center in Nashville, Tennessee and […]

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Mutant gene stops at-risk people from getting Alzheimer’s: Could it lead to treatment?

The APOE4 gene is the most powerful genetic factor driving a person’s risk for developing late-onset Alzheimer’s disease. “It probably increases your risk two or threefold if you have one APOE4 copy, and if you have two APOE4 copies, it probably increases your risk about tenfold,” said Dr. Michael Greicius, a professor of neurology at Stanford Medicine. But that story […]

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Monkeypox has likely spread undetected ‘for some time’: WHO

The WHO said Wednesday that hundreds of monkeypox cases have surfaced beyond the African countries where the disease is typically found, warning the virus has likely been spreading under the radar. “Investigations are ongoing, but the sudden appearance of monkeypox in many countries at the same time suggests there may have been undetected transmission for some time,” World Health Organization […]

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