Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimers disease

A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alzheimer’s disease. Inspired by their previous identification of a genetic variant in the APOE gene that provides extreme resistance against Alzheimer’s disease, the team, which includes investigators from Mass Eye and Ear and Massachusetts General Hospital, […]

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Tom Brady, Gabrielle Union & More Celebs Who’ve Been Shamed for Kissing Their Kids on the Lips

Quite similar to the divisive response public breastfeeding often receives, parents kissing their children on the lips — especially the older they get — causes a large segment of people to lash out in response. While it’s nothing more than an act of love and affection for those who kiss their kids, a shocking amount of people sexualize the innocent […]

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Reducing Cognitive Impairment From SCLC Brain Metastases

For patients with up to 10 brain metastases from small cell lung cancer (SCLC), stereotactic radiosurgery was associated with less cognitive impairment than whole-brain radiation therapy (WBRT) without compromising overall survival, results of the randomized ENCEPHALON (ARO 2018-9) trial suggest. Among 56 patients with one to 10 SCLC brain metastases, 24% of those who received WBRT demonstrated significant declines in […]

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Thousands of US health care workers go on strike in multiple states over wages and staff shortages

Picketing began Wednesday morning at Kaiser Permanente hospitals as some 75,000 health care workers go on strike in Virginia, California and three other states over wages and staffing shortages, marking the latest major labor unrest in the United States. Kaiser Permanente is one of the country’s larger insurers and health care system operators, with 39 hospitals nationwide. The non-profit company, […]

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Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a therapeutic target to overcome neurodegenerative diseases by regulating reactive astrogliosis. Image Credit: Kateryna Kon/Shutterstock.com Background Reactive astrocytes are important players in brain aging and neurodegenerative disorders. They produce LCN-2, a neurotoxin that accumulates in glial cells and […]

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Type 2 diabetes: How testosterone therapy can help manage condition

Researchers say a new study indicates that testosterone replacement therapy helped men with type 2 diabetes. They said testosterone treatment can be beneficial for managing type 2 diabetes because the therapy can improve blood sugar as well as cholesterol levels. They noted that testosterone therapy can also benefit women with type 2 diabetes. A new study suggests that testosterone therapy […]

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