What is the association between long-term salt usage behavior and risk of premature mortality?

In a recent study published in the European Heart Journal, researchers assessed the impact of increased salt consumption on life expectancy. Study: Adding salt to foods and hazard of premature mortality. Image Credit: HandmadePictures/Shutterstock Background The impact of dietary salt intake on human health has always been debated. Recent studies report that sodium intake was inversely related to the risk […]

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Study finds a drop in percentage of methadone-involved overdose deaths from January 2019 to August 2021

The percentage of methadone-involved overdose deaths relative to all drug overdose deaths declined from January 2019 to August 2021, according to a new study. Access to methadone, a medication to treat opioid use disorder, was expanded at the start of the COVID-19 pandemic to allow more patients to take home doses, rather than visit a clinic daily. These data indicate […]

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Benzbromarone Tops Febuxostat for Gout?

Results from a randomized controlled trial conducted in China found low-dose benzbromarone to be more effective in lowering serum urate levels than low-dose febuxostat (Uloric), with a similar safety profile, in gout with renal uric acid underexcretion. Benzbromarone is not approved in the United States because of concerns of acute liver injury but is approved in several other countries, including […]

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How mitochondrial damage ignites the ‘auto-inflammatory fire’

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being. When stressed, damaged or dysfunctional, mitochondria expel their DNA (mtDNA), oxidized and cleaved, into the cytosol—the fluid within a cell in which organelles float—and beyond into […]

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Demand for monkeypox vaccine overwhelms NYC system

Soaring demand for the monkeypox vaccine caused the appointment system to crash in New York City, one of many places where supplies have been running out almost as soon as they arrive. City health officials acknowledged the frustration over the limited supply of the vaccine and vowed to build a “stable appointment infrastructure” as the vaccine supply increases. Infections now […]

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