Liquid biopsies could be used as an early marker of immunotherapy response, study finds

Reviewed Liquid biopsies are blood tests that can serially measure circulating tumor DNA (cell-free DNA that is shed into the bloodstream by dying cancer cells). When used in patients with advanced non-small cell lung cancer undergoing immunotherapy, they may identify patients who could benefit from treatment with additional drugs, according to a phase 2 clinical trial in the U.S. and […]

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Largest ever study on light exposure proves its impact on mental health

The world’s largest study on light exposure and its impact on mental health, with almost 87,000 participants, has found that increased exposure to light at night increases a person’s risk for psychiatric disorders such as anxiety, bipolar and PTSD severity as well as self-harm. Importantly, the study also found that increasing exposure to daytime light can act like a non-pharmacological […]

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McLean Hospital partners with Rippl Care to address mental health needs of seniors with dementia

Reviewed To address a crisis of unmet mental health needs among seniors with dementia and their family caregivers amid a shortage of mental health providers with expertise treating this population, McLean Hospital, a member of Mass General Brigham, has entered into an agreement to offer strategic advisory services and professional education to Rippl Care. Rippl provides specialty dementia care and […]

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Two-year-old Cambodian girl dies from bird flu

A two-year-old Cambodian girl has died from bird flu, the health ministry said Monday night, the second death recorded in the country in two days. The World Health Organization has called for vigilance after the virus was detected in mammals, but has stressed that the risk to humans is low. The health ministry said tests on Monday confirmed the unnamed […]

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Health experts redefine cardiovascular disease risk, prevention and management

Reviewed Health experts are redefining cardiovascular disease (CVD) risk, prevention and management, according to a new American Heart Association presidential advisory published today in the Association's flagship journal Circulation. Various aspects of cardiovascular disease that overlap with kidney disease, Type 2 diabetes and obesity support the new approach. For the first time, the American Heart Association defines the overlap in […]

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Are Women and Men With Rheumatism Treated Equally?

LEIPZIG, Germany — Women eat more healthily, visit their physician more often, and accept offers of prophylactic treatment more frequently than their male counterparts. Nevertheless, they are generally diagnosed with a rheumatic disease much later. “With systemic sclerosis for example, diagnosis occurs a whole year later than for male patients,” said Uta Kiltz, MD, senior physician at the Ruhrgebiet Rheumatism […]

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Immature immune cells near dural sinuses linked to neonatal viral meningoencephalitis

In a recent article in Science Immunology, researchers used the lymphocytic choriomeningitis virus (LCMV) model to examine virus propagation within central nervous systems (CNSs) during systemic infection. They evaluated the structural and functional differences in the CNS borders of four- and eight-week-old adult mice (P28) and male & female postnatal day seven (P7) neonates using the LCMV model as it does […]

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Redefining heart disease risk, prevention and management

Health experts are redefining cardiovascular disease (CVD) risk, prevention and management, according to a new American Heart Association presidential advisory published today in the journal Circulation. Various aspects of cardiovascular disease that overlap with kidney disease, type 2 diabetes and obesity support the new approach. For the first time, the American Heart Association defines the overlap in these conditions as […]

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Neonatal ICU mystery: Unraveling the secrets of the prevalent Staphylococcus strain

In a recent study published in Microbial Genomics, researchers investigated the genomes of a group of Staphylococcus capitis isolates from neonates. Study: Characterisation of neonatal Staphylococcus capitis NRCS-A isolates compared with non NRCS-A Staphylococcus capitis from neonates and adults. Image Credit: Dmitry Kalinovsky/Shutterstock.com Background NRCS-A, a clone of S. capitis, is prevalent among newborns, a vulnerable population prone to late-onset […]

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