Serum albumin could prevent amyloid fibril formation in dialysis patients

Dialysis is a lifesaving technique that artificially filters blood; however, it has some harmful side effects. Now, researchers from Japan have found that monitoring a normal blood component could help prevent one of the more serious complications of long-term dialysis. In a study in Nature Communications, researchers from Osaka University reveal that a high concentration of a key molecule found […]

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Stroke Care Stable After COVID-Linked Move to Telemedicine

The clinical care and short-term outcomes after a minor ischemic stroke or transient ischemic attack (TIA) remained stable in Ontario, Canada, following the widespread implementation of telemedicine in 2020, according to a new report. Clinical outcomes, access to outpatient visits, and medication renewals were comparable to those seen before the COVID-19 pandemic prompted virtual visits. “TIAs often precede major disabling […]

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Online Tool IDs People With Genetic Mutations Linked to Cancer

A new online tool can quickly and accurately identify individuals who may benefit from genetic testing because they likely carry pathogenic germline variants (PGVs) in a diverse spectrum of cancer susceptibility genes. The PREMMplus online tool was developed and validated by researchers at Dana-Farber Cancer Institute in Boston using three cohorts involving more than 30,000 individuals who had undergone multigene […]

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Severe COVID-19–Related Outcomes Found Worse in Men With RA

A retrospective study that analyzed sex disparities in patients with COVID-19 and rheumatoid arthritis found that men had more baseline comorbidities and increased risk of COVID-19–related outcomes, compared with females. “Differences in genetics between sex and sex steroid hormones may play a role in predisposition to COVID-19 infection as well as modulating the disease progression,” according to Xiaofeng Zhou, PhD, […]

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New noninvasive neuroimaging method for direct mapping of neuronal activity in a living mouse's brain

A new noninvasive neuroimaging method dubbed DIANA (direct imaging of neuronal activity) allows direct mapping of neuronal activity in a living mouse's brain at high resolution, researchers report. According to the study authors, the ability to image neuronal activity directly and at such high spatial and temporal resolutions could open new avenues in brain science by providing a deeper understanding […]

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Kidney Disease; Updated COVID Booster; and Renaming Monkeypox

Kidney Disease Plays Favorites With Sex Despite having lower kidney function than men do at age 50, women’s kidney function holds steady over time, whereas it drops more rapidly in men, according to new research. Puzzling contradiction: Men undergo dialysis more frequently and require more kidney transplants than do women despite having seemingly healthier kidneys. Methodology: The researchers recruited 1837 […]

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Study: 70% of junior doctors reported severe depression, anxiety or stress during Covid-19 pandemic

Poor working conditions during the Covid-19 pandemic were factors in nearly half of junior doctors reporting symptoms of extremely severe depression, according to a new study led by the University of Surrey. The study found that 70 per cent of respondents reported feeling severe or extremely severe levels of depression, anxiety or stress symptoms while they were helping the NHS […]

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Researchers identify a previously unknown mitochondrial disease in identical twins

In a set of identical twins, investigators led by researchers at Massachusetts General Hospital (MGH) and Children's Hospital Philadelphia (CHOP) have identified a mitochondrial disease not previously reported. Diseases that affect mitochondria-;specialized compartments within cells that contain their own DNA and convert the food we eat into energy needed to sustain life-;typically interfere with mitochondrial function, but in these two […]

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Intermittent movement behavior at large, crowded events increases disease transmission risk

What is the typical movement behavior of visitors to large events, such as concerts, and what does this mean for the risk of spreading infectious diseases like COVID-19? A group of researchers from the Informatics Institute at the University of Amsterdam, together with an epidemiologist from the Utrecht University, set out to investigate using data from events in a large […]

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