Irregular and long menstrual cycles are associated with increased rates of cardiovascular disease (CVD), according to a study published online Oct. 25 in JAMA Network Open. Yi-Xin Wang, M.D., Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues explored associations between menstrual cycle characteristics across the reproductive life span and the risk for CVD. The […]

It is estimated that around 10% of the US population has peanut allergies, a medical emergency that can be treated but not cured. Compared to those without allergies, these individuals are at a greater risk of anaphylaxis. Hence, there is a need to develop novel therapies to treat peanut and other food allergies. A recent Frontiers in Immunology journal study by University […]

One of the biggest developments in healthcare has been using AI to support clinical routine, which has unlocked new and unprecedented levels of precision in prevention, diagnosis and treatment. The goal of AI is to relieve physicians of considerable administrative burden and, ultimately, to save time and reduce costs when optimally embedded in the workflow. It also supports clinicians in […]

Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development. The once radical idea that such changes in gene expression can be inherited now has a growing body of evidence behind it, but the mechanisms involved remain poorly understood. A new study by researchers at UC Santa Cruz […]

The immune checkpoint inhibitors, including anti-PD-1 and anti-PD-L1 antibodies (αPD-1 and αPD-L1), have revolutionized tumor immunotherapy. Although αPD-1 and αPD-L1 show excellent efficacy in various tumor types, even in patients with advanced tumors, only 10–30% of patients respond to αPD-1 and αPD-L1 therapy due to primary resistance. Extracellular vesicles (EVs) are highly involved in the progression of the tumor. PD-L1+ […]

Masks can be scary on Halloween, but more so when they come with scrubs, scalpels, and God complexes. In March, Medscape readers chose their favorite characters and performers in the Hollywood healthcare system. As a Halloween treat, we follow up with a dozen of our favorite Evil Doctors from a deep bench (and no, Dr Evil didn’t go to medical […]

Inflation is running high around the globe, largely fueled by Russia’s war in Ukraine and the COVID pandemic. As a result, many households are having to choose between eating and heating. Deprivation has a terrible immediate effect on children—as anyone who has experienced real hunger knows—but it can also affect things like impulsive behavior in later life. “Trait impulsivity”, the […]

How safe are the cutting edge treatments being offered by private clinics? Experts fear thousands are being spent on procedures that may be unproven and even harmful With NHS waiting lists at record levels, more of us are being driven to spend precious money on private medical treatments. With a staggering 6.7 million people currently waiting for hospital treatment in […]

Scientists at UC San Francisco (UCSF) have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology. They theorize that males and females took opposing paths in a tradeoff between immunity and metabolism that occurs in the liver. This helped males fight bacterial infections from wounds received in dominance fights, while helping females store subcutaneous […]

Written by Lauren Potts When it comes to losing, writer Lauren Potts is as sore as they come (“no more so than when I’ve lost a game of Monopoly Deal to the in-laws,” she confesses). So why are some adults such sore losers – and how do you become a better one?  “It’s just a game” is not a lesson […]