The influenza virus and its influence on blood stem cells and coagulation

Virus-induced respiratory infections can become life-threatening. A team at the Paul-Ehrlich-Institut, together with researchers in Heidelberg, has discovered that flu virus infection limited to the lungs also leads to the activation of blood stem cells and the increased formation of platelets. Platelets can cause thrombosis, as has been shown in severe cases of COVID-19. The messenger substances interleukin-1 and interleukin-6 […]

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Scientists develop mathematical model to evaluate potential cancer treatment protocols

A Rochester Institute of Technology scientist helped develop a new mathematical model that could aid doctors and patients assessing different approaches for treating metastatic cancer. Assistant Professor Nourridine Siewe from RIT’s School of Mathematical Sciences is the lead author on a paper published in the Journal of Theoretical Biology outlining the new method. In recent years, drugs called immune checkpoint […]

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New way of reprogramming immune cells shown to work in melanoma

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard-to-treat and devastating skin cancer, melanoma. The University of Bristol-led discovery, published in Advanced Science today [31 October], demonstrates a new way to clear early stage pre-cancerous and even late-stage tumor cells. Using miniature artificial capsules called […]

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CRISPR Gene Editing Takes Next Step in TTR Amyloidosis

Treatment with the investigational CRISPR-Cas9 gene-editing therapy, NTLA-2001, led to rapid responses in patients with transthyretin (TTR) amyloidosis with cardiomyopathy (ATTR-CM), interim phase 1 results show. Serum levels of the disease-causing TTR protein were reduced by at least 90% at day 28 with a single infusion of NTLA-2001 at two different doses, with reductions sustained across 4 to 6 months’ […]

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Study finds earlier mammograms for women with family history of breast cancer may not be needed

A new study released in the journal Cancer reconsiders guidelines for when to start screening with mammograms if a woman has a mother, sister, or daughter who was diagnosed with breast cancer. Women with a first-degree family relative diagnosed with breast cancer, who are otherwise at average risk, are often advised to get screened 10 years earlier than the relative’s […]

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COVID-Related Claims Filed Against 100 French Physicians

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. PARIS — In 2021, the Mutual Insurance Company for French Healthcare Professionals (MACSF) received about 100 claims based on COVID-19. The claims were related to nosocomial infections, delays in treatment, and even diagnostic errors made during e-consultations. This was a change from the previous year, which had seen a significant decrease […]

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‘Smart’ bandages could help with wound care

Around 7 million people in the U.S. suffer from chronic wounds that don’t heal as they should, costing billions of dollars per year in health care costs to treat them—not to mention the human cost to patients’ well-being. New research from Binghamton University’s Thomas J. Watson College of Engineering and Applied Science takes an initial step toward better understanding of […]

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One in three Canadians developed severe loneliness amidst the second wave of COVID-19

Pandemic-induced public health measures, such as social distancing and stay-at-home orders, while successful in decreasing the transmission of COVID-19, could exacerbate pre-existing mental health challenges, including loneliness, one of the major public health concerns in pre-pandemic times. A new nationwide study published in the Journal of Affective Disorders estimated that in Canada, 34.7% percent of the population, or just over […]

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