WASHINGTON — In patients with cirrhosis associated with non-alcoholic steatohepatitis (NASH), 1 year of treatment with the investigational oral thyromimetic agent resmetirom (MGL-3196) was safe and effective at lowering markers of both cardiovascular risk and NASH fibrosis, new research has found. Two cohorts comprising a total of 180 patients with well-compensated NASH cirrhosis enrolled in an open-label arm of the […]

British Heart Foundation: Understanding blood clots We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Many underlying factors can cause clotting, such as your blood vessels stiffening. Healthy arteries […]

Treatment wth olpasiran, a small interfering RNA product targeting lipoprotein (a) synthesis, led to a profound and sustained reduction in Lp(a) concentration when administered every 12 weeks in a new phase 2 study. The OCEAN(a)-DOSE study showed that doses of 75 mg or more of olpasiran every 12 weeks led to reductions of more than 95% in levels of Lp(a) […]

Birth control options have improved over the decades. Oral contraceptives are now safer, with fewer side effects. Intrauterine devices can prevent pregnancy 99.6% of the time. But no prescription drug or medical device works flawlessly, and people’s use of contraception is inexact. “No one walks into my office and says, ‘I plan on missing a pill,’” said obstetrician-gynecologist Dr. Mitchell […]

Up to 90% of all marine life across the globe could face extinction by 2100 if drastic measures aren’t taken to reduce greenhouse gases, according to an international team of researchers reporting in Nature Climate Change. What to know: Under the high greenhouse emissions currently being observed, global atmospheric temperatures will increase 3-5 °C in the next 80 years, and […]

Text messages, app alerts and emails—so-called “digital nudges”—are effective at pushing us to do things, even exercise. New University of Minnesota research shows these actions used by corporate wellness programs lead to increased exercise among participants. A majority of large employers offer wellness programs to encourage healthy, active lifestyles among their employees. However, these programs often face low participation. Carlson […]

A small new study suggests — but doesn’t prove — that exposure to Wi-Fi signals from cell phones in pants pockets could disrupt male fertility. Researchers found that sperm placed next to an in-use iPhone on the Wi-Fi setting over 6 hours had less motility (50% vs. 38%, P = .024) and viability (60% vs. 47%, P = .003) than those set to 4G […]

Changing the wording about expiration dates on perishable food items – which is currently unregulated and widely variable – could help reduce food waste, according to a new Cornell University-led study. A survey of consumers found that certain wording – "best by," as opposed to "best if used by," for example – had the potential to reduce food waste, but […]

Cambridge researchers are taking part in the world’s first clinical trial of red blood cells that have been grown in a laboratory for transfusion into another person. The manufactured blood cells were grown from stem cells from donors. The red cells were then transfused into volunteers in the RESTORE randomized controlled clinical trial. This is the first time in the […]

Mike Tindall confirmed for I’m a Celebrity We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info The former rugby player described his father as a “typical northern bloke” who […]