Talquetamab: New drug may offer hope for those with hard-to-treat blood cancer

Multiple myeloma is the second-most-common blood cancer, but is currently regarded as not curable. In multiple myeloma, plasma cells, a part of the immune system, multiply out of control and prevent the formation of other blood cells. Current treatments include chemotherapy and stem cell transplants. In phase 2 trials of a new treatment, talquetamab, around 73% of participants showed a […]

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Fathers who drink heavily report less positive involvement with their children

Fathers who acknowledge binge drinking are less involved with their children, according to new research in several countries that have traditionally been understudied. Globally, men are increasingly involved in children’s development. The latest analysis, in Alcoholism: Clinical & Experimental Research, explores fathers’ binge drinking in relation to the quality of their parenting, and suggests that preventing or treating heavy alcohol […]

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Rheumatology Workforce Shortage Demands Multipronged Approach

PHILADELPHIA – New rheumatology fellowships in underserved areas. Rheumatology training for nonspecialists. Telemedicine training, tools, and resources. These are a few of the remedies the American College of Rheumatology’s new Workforce Solutions Committee has concocted to address a shrinking U.S. rheumatology workforce in the face of a rising population of patients with rheumatologic diseases. In two sessions at the ACR’s annual […]

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Study finds that insomnia could cause lower back pain and vice versa

Throughout the course of their life, most humans are likely to experience some form of lower back pain. This pain is sometimes associated with injuries, chronic back issues, medical conditions, the menstrual cycle or pregnancy, and other underlying physiological causes. In many cases, however, pinpointing the origin of lower back pain is difficult, despite its severity and its potential impact […]

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PhoreMost and ThinkCyte collaborate to advance AI based drug discovery

PhoreMost Ltd., the UK-based biopharmaceutical company dedicated to ‘Drugging the Undruggable®’ disease targets, and ThinkCyte K.K, a biotechnology company pioneering novel cell analysis and sorting instruments, today announced a strategic research partnership aimed at advancing modern phenotypic drug screening using artificial intelligence (AI). The partnership leverages both companies’ distinctive technologies in high-throughput drug discovery, PhoreMost’s next-generation phenotypic screening platform, SITESEEKER®, […]

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Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

Scientists have identified an immunogenic epitope at the furin cleavage site of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that induces robust antibody responses in coronavirus disease 2019 (COVID-19) patients. In their study published in the journal eBioMedicine, the researchers also identified a monoclonal antibody that binds to this epitope and protects mice against SARS-CoV-2 infection. Study: Identification of an immunogenic […]

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Large, real-world study finds COVID-19 vaccination more effective than natural immunity

In one of the first large, real-world studies comparing the effectiveness of COVID-19 vaccines versus natural immunity in protecting against death, hospitalizations and emergency department (ED) visits for any cause, including COVID, research-scientists from Regenstrief Institute, Indiana University School of Medicine and Vanderbilt University Medical Center report that people of all age groups benefited significantly more from vaccination than natural […]

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