Single nucleus RNAseq of mouse and human R6/2 and HD samples. a Illustration of workflow used for this study. After frozen tissue is microdissected from the Cingulate, Caudate, and nucleus Accumbens from 66 samples from 29 human donors (3 grade I, 4 grade II, 4 grade III, 3 grade IV, 5 juvenile-onset HD, and 10 matched controls), or the striatum […]

Retinal age, a validated biomarker of overall aging, shows efficacy as a potentially important, non-invasive biomarker to predict the risk of end-stage kidney disease (ESKD), new research shows. “Retinal imaging is highly amendable to repeated and longitudinal assessments, facilitating long-term monitoring for chronic kidney disease [CKD], which, coupled with the potential of retinal age being a predictor of mortality, could […]

Some solid food diets may aid in the treatment of inflammatory bowel disease (IBD), though the overall quality of evidence remains low and additional data is needed, according to a new report. For Crohn’s disease, a diet low in refined carbohydrates and a symptoms-guided diet appeared to help with remission, yet reduction of refined carbohydrates or red meat didn’t reduce […]

We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info A paramedic has told how she spends, on average, “five to six hours” of her shift waiting with patients before […]

Below is a brief roundup of news and story ideas from the experts at UCLA Health. For more information on these stories or for help on other stories, please contact us at [email protected] Journal scan The link between obesity, the brain, and stroke Obesity, a growing global problem, increases the risk for stroke and vascular brain injury with long-term consequences […]

Strep A: Manchester pharmacist discusses supply issues We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info The various lockdowns of the last two years helped control the spread of […]

Ever noticed that just when you’re beginning to feel on the verge of a cold, you break into mouth ulcers? You’re not the only one, says writer Kat Storr. I always know when I’ve been burning the candle at both ends. It’s not just the tiredness that hits me but, and this sounds weird, my tongue will let me know. […]

An analysis of more than 100,000 colorectal cancer cases and 154,000 healthy controls published in Nature Genetics uncovered hundreds of signals that may serve as new treatment and prevention targets. This study is twice as large as previous genome-wide association studies, according to the paper. The collaboration included researchers affiliated with hundreds of studies and institutions across Europe, North America […]

This article contains affiliate links. We will earn a small commission on purchases made through one of these links but this never influences our experts’ opinions. Products are tested and reviewed independently of commercial initiatives. With Christmas and 2023 fast approaching, one of your goals next year may be to take better care of your body and mind. But, instead […]

ICAP at Columbia University Mailman School of Public Health has released results from Round Two of the SILVER Study, providing insight into the challenges presented by COVID-19 to older adults living at home in New York City. The results reveal a range of key issues—from mental health effects to access to reliable information about vaccines—that older New Yorkers have encountered […]