FDA Says No to Accelerated Approval for Alzheimer’s Drug

The US Food and Drug Administration (FDA) has denied accelerated approval for the investigational anti-amyloid donanemab (Eli Lilly) for the treatment of early Alzheimer’s disease (AD) because of insufficient data, the manufacturer has announced. In a press release, the company reported the FDA issued a complete response letter requesting that Lilly provide data from at least 100 patients who received […]

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Nearly 9 in 10 trans youth say recent wave of anti-LGBTQ policies negatively affected their mental health

The recent explosion in anti-LGBTQ rhetoric across the country is dramatically affecting LGBTQ youth—especially transgender and nonbinary kids and young adults—according to a poll released Thursday. An overwhelming majority of queer and transgender youth in the U.S. say the growing number of policies restricting their rights have negatively impacted their mental health, leading to feelings of anxiety, fear, sadness and […]

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Size of Meals, Not Timing, Linked to Weight Loss

The number of daily meals, but not the timing between first and last daily meals, was significantly associated with weight changes over a 6-year period, in a prospective study of more than 500 adults. Some studies suggest that timing food intake – through time-restricted eating or intermittent fasting – can promote weight loss, but these strategies have yielded similar weight […]

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Might poor emotional regulation increase dementia risk?

Researchers have recently investigated how older adults recover from negative stimuli. They found that older adults prone to rumination and negative thinking display increased connectivity between brain areas linked to emotional and autobiographical processing. They are now investigating whether mindfulness or “compassionate” meditation might help reduce dementia risk, since chronic negative emotions are associated with neurodegenerative conditions. Studies show that […]

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Series: More cooperation needed among various types of health organizations to protect against public health crises

The COVID-19 pandemic has exposed weaknesses in the world’s global health security networks, says a new four-paper series published in The Lancet. The series authors argue that we must implement a “One Health” approach globally, with human, animal and environmental health organizations working together to prevent, monitor and respond to public health emergencies. In The Lancet Series on One Health […]

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