Researchers uncover mechanisms of brexanolone and the role of inflammation in post-partum depression

Post-partum depression (PPD) develops after childbirth and affects both the mother’s and the infant’s health by preventing healthy bonding. Women with PPD experience intense anxiety, feelings of depression, sleeplessness, inability to care for their child, and risk for suicide. Brexanolone, an IV infusion comprised of a derivative of progesterone, was approved by the U.S. Food and Drug Administration for the […]

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Adjuvant Nivolumab as Standard of Care in Resected Bladder Cancer

SAN FRANCISCO — New findings lend further support to adjuvant nivolumab (Opdivo) as a standard of care for patients with metastatic urothelial cancer. Extended follow-up data from the phase 3 CheckMate 274 trial continue to show that, compared with placebo, nivolumab improves disease-free survival, non-urothelial tract recurrence-free survival (NUTRFS), and distant metastasis-free survival (DMFS) in patients with high-risk, muscle-invasive urothelial […]

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Addiction researchers denounce Australia’s NHMRC statement on e-cigarettes

Eleven top international addiction scientists argue that the 2022 statement on e-cigarettes issued by Australia’s peak health and medical body, the National Health and Medical Research Council (NHMRC), fails to meet the high scientific standard expected of a leading national scientific body. The NHMRC statement, published in June 2022, aims to provide “public health advice on the safety and impacts […]

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Temperature changes in the brain found to affect neuronal activity

Last summer, devastating wildfires raged across frozen regions in Siberia, Alaska, and Canada. They were caused in part by rising global temperatures, which accelerated the ability of bacteria in the soil to metabolize plant and animal matter. These environmental phenomena demonstrated a basic principle of physics—temperature is one of the main components of a chemical reaction and even seemingly small […]

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EU-funded PANDASIA project investigates how potential pandemics emerge

The PANDASIA project investigates how infectious diseases are transmitted between animals, humans and environment and how potential pandemics emerge. The findings will be used to enhance health literacy in different target groups in Thailand and Europe. Emerging infectious diseases, which are caused by zoonotic pathogens such as viruses and bacteria are transmitted between animals and humans, pose an increasing threat […]

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‘Super premature’: Scientists split over timing of tick for medicinal psychedelics

Australia’s decision to allow the prescription of medicinal psychedelics is being hailed by some researchers as an opportunity to lead the world in innovative mental health treatments, but others are worried this month’s ruling was premature. From July, Australia will be among the first places in the world to allow authorised psychiatrists to prescribe psilocybin (the active chemical in magic […]

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